Profenofos

Target genes for Profenofos is obtained based on ToxCast assay component endpoints.
Chemical nameGene identifierToxCast assay component endpoint name
ProfenofosNR1H3ATG_DR4_LXR_CIS_dn
ProfenofosCREB3ATG_CRE_CIS_up
ProfenofosCEBPBATG_C_EBP_CIS_up
ProfenofosCOL3A1BSK_hDFCGF_CollagenIII_down
ProfenofosCSF1BSK_LPS_MCSF_down
ProfenofosCSF1BSK_hDFCGF_MCSF_down
ProfenofosCYP1A1CLD_CYP1A1_24hr
ProfenofosCYP1A2CLD_CYP1A2_48hr
ProfenofosCYP1A2NVS_ADME_hCYP1A2
ProfenofosCYP1A2CLD_CYP1A2_24hr
ProfenofosCYP2B6CLD_CYP2B6_6hr
ProfenofosCYP2B6CLD_CYP2B6_24hr
ProfenofosCYP2B6CLD_CYP2B6_48hr
ProfenofosCYP2B6NVS_ADME_hCYP2B6
ProfenofosCYP2C19NVS_ADME_hCYP2C19
ProfenofosCYP2C9NVS_ADME_hCYP2C9
ProfenofosCYP2C18NVS_ADME_hCYP2C18
ProfenofosCYP3A4CLD_CYP3A4_24hr
ProfenofosCYP3A4CLD_CYP3A4_48hr
ProfenofosCYP3A4CLD_CYP3A4_6hr
ProfenofosEGR1ATG_EGR_CIS_up
ProfenofosELANENVS_ENZ_hElastase
ProfenofosESR1ATG_ERE_CIS_up
ProfenofosESR1TOX21_ERa_BLA_Antagonist_ratio
ProfenofosESR1OT_ER_ERaERb_0480
ProfenofosESR1ATG_ERa_TRANS_up
ProfenofosESR2OT_ER_ERaERb_0480
ProfenofosESR2OT_ER_ERbERb_0480
ProfenofosESR2TOX21_ERb_BLA_Antagonist_ratio
ProfenofosESRRATOX21_ERR_Antagonist
ProfenofosNR3C1NVS_NR_hGR
ProfenofosHLA-DRABSK_BE3C_HLADR_down
ProfenofosIL6BSK_CASM3C_IL6_up
ProfenofosCXCL8BSK_SAg_IL8_down
ProfenofosCXCL8BSK_LPS_IL8_down
ProfenofosCXCL10BSK_BE3C_IP10_down
ProfenofosCXCL10BSK_hDFCGF_IP10_down
ProfenofosARTOX21_AR_BLA_Antagonist_ratio
ProfenofosARTOX21_AR_LUC_MDAKB2_Antagonist_10nM_R1881
ProfenofosAROT_AR_ARSRC1_0480
ProfenofosARTOX21_AR_LUC_MDAKB2_Antagonist_0.5nM_R1881
ProfenofosCXCL9BSK_SAg_MIG_down
ProfenofosACHENVS_ENZ_hAChE
ProfenofosMMP1BSK_BE3C_MMP1_up
ProfenofosMTF1ATG_MRE_CIS_up
ProfenofosNFIAATG_NFI_CIS_up
ProfenofosNFE2L2ATG_NRF2_ARE_CIS_up
ProfenofosNFKB1ATG_NF_kB_CIS_up
ProfenofosOPRM1NVS_GPCR_hOpiate_mu
ProfenofosSERPINE1BSK_BE3C_PAI1_down
ProfenofosPGRNVS_NR_hPR
ProfenofosPGRTOX21_PR_BLA_Antagonist_ratio
ProfenofosPLATBSK_BE3C_tPA_down
ProfenofosPOU2F1ATG_Oct_MLP_CIS_up
ProfenofosUGT1A1CLD_UGT1A1_48hr
ProfenofosUGT1A1CLD_UGT1A1_24hr
ProfenofosBCHENVS_ENZ_hES
ProfenofosRXRAOT_NURR1_NURR1RXRa_0480
ProfenofosCCL2BSK_4H_MCP1_down
ProfenofosCCL2BSK_SAg_MCP1_down
ProfenofosSELEBSK_3C_Eselectin_down
ProfenofosSELEBSK_SAg_Eselectin_down
ProfenofosSELEBSK_LPS_Eselectin_down
ProfenofosSELPBSK_4H_Pselectin_down
ProfenofosSLC5A5NIS_RAIU_inhibition
ProfenofosSREBF1ATG_SREBP_CIS_up
ProfenofosTHBDBSK_CASM3C_Thrombomodulin_up
ProfenofosTSPONVS_MP_hPBR
ProfenofosNR1H2ATG_DR4_LXR_CIS_dn
ProfenofosVCAM1BSK_4H_VCAM1_down
ProfenofosVCAM1BSK_hDFCGF_VCAM1_down
ProfenofosVCAM1BSK_LPS_VCAM1_down
ProfenofosVDRATG_VDRE_CIS_up
ProfenofosXBP1ATG_Xbp1_CIS_up
ProfenofosNR1I2ATG_PXRE_CIS_up
ProfenofosCD38BSK_SAg_CD38_down
ProfenofosCD40BSK_SAg_CD40_down
ProfenofosCD69BSK_SAg_CD69_down
ProfenofosNR1I3NVS_NR_hCAR_Antagonist
ProfenofosNR1I3TOX21_CAR_Agonist
ProfenofosNR1H4OT_FXR_FXRSRC1_0480

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