Triadimefon

Target genes for Triadimefon is obtained based on ToxCast assay component endpoints.
Chemical nameGene identifierToxCast assay component endpoint name
TriadimefonNACEETOX_H295R_PROG_dn
TriadimefonESR1CEETOX_H295R_ESTRADIOL_dn
TriadimefonESR1CEETOX_H295R_TESTO_dn
TriadimefonESR1CEETOX_H295R_ESTRONE_dn
TriadimefonNACEETOX_H295R_TESTO_dn
TriadimefonNACEETOX_H295R_ANDR_dn
TriadimefonCREB3ATG_CRE_CIS_up
TriadimefonCEBPBATG_C_EBP_CIS_up
TriadimefonCHRM2NVS_GPCR_hM2
TriadimefonCHRM3NVS_GPCR_hM3
TriadimefonCHRM4NVS_GPCR_hM4
TriadimefonLTB4RNVS_GPCR_hLTB4_BLT1
TriadimefonCYP1A1CLD_CYP1A1_24hr
TriadimefonCYP1A1CLD_CYP1A1_6hr
TriadimefonCYP1A1NVS_ADME_hCYP1A1
TriadimefonCYP1A2CLD_CYP1A2_48hr
TriadimefonCYP1A2CLD_CYP1A2_6hr
TriadimefonCYP1A2CLD_CYP1A2_24hr
TriadimefonCYP2B6CLD_CYP2B6_6hr
TriadimefonCYP2B6CLD_CYP2B6_24hr
TriadimefonCYP2B6CLD_CYP2B6_48hr
TriadimefonCYP2C19NVS_ADME_hCYP2C19
TriadimefonCYP2C9NVS_ADME_hCYP2C9
TriadimefonCYP2C18NVS_ADME_hCYP2C18
TriadimefonCYP3A4CLD_CYP3A4_24hr
TriadimefonCYP3A4CLD_CYP3A4_6hr
TriadimefonCYP3A4NVS_ADME_hCYP3A4
TriadimefonCYP3A4CLD_CYP3A4_48hr
TriadimefonCYP19A1TOX21_Aromatase_Inhibition
TriadimefonCYP19A1NVS_ADME_hCYP19A1
TriadimefonEGR1ATG_EGR_CIS_up
TriadimefonAHRATG_Ahr_CIS_up
TriadimefonAHRTOX21_AhR_LUC_Agonist
TriadimefonESR1OT_ER_ERaERb_1440
TriadimefonESR1OT_ER_ERaERb_0480
TriadimefonESR1CEETOX_H295R_ESTRADIOL_dn
TriadimefonESR1ATG_ERE_CIS_up
TriadimefonESR1ATG_ERa_TRANS_up
TriadimefonESR1TOX21_ERa_LUC_VM7_Agonist
TriadimefonESR1CEETOX_H295R_ESTRONE_dn
TriadimefonESR1ACEA_ER_80hr
TriadimefonESR2CEETOX_H295R_ESTRONE_dn
TriadimefonESR2OT_ER_ERaERb_1440
TriadimefonESR2CEETOX_H295R_ESTRADIOL_dn
TriadimefonESR2OT_ER_ERaERb_0480
TriadimefonESR2OT_ER_ERbERb_1440
TriadimefonESRRATOX21_PGC_ERR_Antagonist
TriadimefonESRRATOX21_ERR_Antagonist
TriadimefonFOSATG_AP_1_CIS_up
TriadimefonNR3C1CEETOX_H295R_CORTISOL_dn
TriadimefonNR3C1CEETOX_H295R_11DCORT_dn
TriadimefonNR3C1NVS_NR_hGR
TriadimefonHLA-DRABSK_3C_HLADR_down
TriadimefonARCEETOX_H295R_TESTO_dn
TriadimefonARACEA_AR_antagonist_80hr
TriadimefonARCEETOX_H295R_ANDR_dn
TriadimefonARNVS_NR_hAR
TriadimefonARTOX21_AR_LUC_MDAKB2_Antagonist_0.5nM_R1881
TriadimefonJUNATG_AP_1_CIS_up
TriadimefonESR1CEETOX_H295R_TESTO_dn
TriadimefonESR1CEETOX_H295R_ESTRADIOL_dn
TriadimefonESR1CEETOX_H295R_ESTRONE_dn
TriadimefonNACEETOX_H295R_TESTO_dn
TriadimefonNACEETOX_H295R_ESTRONE_dn
TriadimefonNACEETOX_H295R_ESTRADIOL_dn
TriadimefonSMAD1ATG_BRE_CIS_up
TriadimefonARCEETOX_H295R_TESTO_dn
TriadimefonARCEETOX_H295R_ANDR_dn
TriadimefonNR3C2CEETOX_H295R_CORTISOL_dn
TriadimefonNR3C2CEETOX_H295R_11DCORT_dn
TriadimefonMTF1ATG_MRE_CIS_up
TriadimefonNFE2L2ATG_NRF2_ARE_CIS_up
TriadimefonPAX6ATG_Pax6_CIS_up
TriadimefonPGRTOX21_PR_BLA_Antagonist_ratio
TriadimefonPGRCEETOX_H295R_PROG_dn
TriadimefonPGRCEETOX_H295R_OHPROG_dn
TriadimefonPGRCEETOX_H295R_OHPREG_dn
TriadimefonPOU2F1ATG_Oct_MLP_CIS_up
TriadimefonPPARAATG_PPRE_CIS_up
TriadimefonPPARDATG_PPRE_CIS_up
TriadimefonPPARGATG_PPARg_TRANS_up
TriadimefonPPARGATG_PPRE_CIS_up
TriadimefonRARAATG_RARa_TRANS_up
TriadimefonRARAATG_DR5_CIS_up
TriadimefonRARBATG_DR5_CIS_up
TriadimefonRARGATG_DR5_CIS_up
TriadimefonSLC6A3NVS_TR_hDAT
TriadimefonTSPONVS_MP_hPBR
TriadimefonTP53TOX21_p53_BLA_p5_ratio
TriadimefonTSHRTOX21_TSHR_Agonist_ratio
TriadimefonVDRATG_VDRE_CIS_up
TriadimefonNACEETOX_H295R_TESTO_dn
TriadimefonNACEETOX_H295R_ANDR_dn
TriadimefonNR1I2ATG_PXR_TRANS_up
TriadimefonNR1I2ATG_PXRE_CIS_up
TriadimefonNR1I2NVS_NR_hPXR
TriadimefonNR1I3ATG_PBREM_CIS_up
TriadimefonNR1H4OT_FXR_FXRSRC1_0480

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We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.