Malathion

Target genes for Malathion is obtained based on ToxCast assay component endpoints.
Chemical nameGene identifierToxCast assay component endpoint name
MalathionNACEETOX_H295R_PROG_up
MalathionCREB3ATG_CRE_CIS_up
MalathionCEBPBATG_C_EBP_CIS_up
MalathionADORA1NVS_GPCR_hAdoRA1
MalathionADORA2ANVS_GPCR_hAdoRA2a
MalathionCYP1A1CLD_CYP1A1_6hr
MalathionCYP1A1NVS_ADME_hCYP1A1
MalathionCYP1A2NVS_ADME_hCYP1A2
MalathionCYP1A2CLD_CYP1A2_48hr
MalathionCYP1A2CLD_CYP1A2_24hr
MalathionCYP1A2CLD_CYP1A2_6hr
MalathionCYP2A6NVS_ADME_hCYP2A6
MalathionCYP2B6NVS_ADME_hCYP2B6
MalathionCYP2C19NVS_ADME_hCYP2C19
MalathionCYP2C9NVS_ADME_hCYP2C9
MalathionCYP2C18NVS_ADME_hCYP2C18
MalathionCYP2D6NVS_ADME_hCYP2D6
MalathionCYP2J2NVS_ADME_hCYP2J2
MalathionCYP3A4NVS_ADME_hCYP3A4
MalathionCYP19A1NVS_ADME_hCYP19A1
MalathionEGR1ATG_EGR_CIS_up
MalathionAHRATG_Ahr_CIS_up
MalathionESR1ATG_ERE_CIS_up
MalathionESR1ATG_ERa_TRANS_up
MalathionESR2TOX21_ERb_BLA_Antagonist_ratio
MalathionFOSATG_AP_1_CIS_up
MalathionNR3C1ATG_GRE_CIS_dn
MalathionHLA-DRABSK_3C_HLADR_down
MalathionFOXA2ATG_FoxA2_CIS_up
MalathionCXCL10BSK_hDFCGF_IP10_down
MalathionARNVS_NR_hAR
MalathionARACEA_AR_antagonist_80hr
MalathionAROT_AR_ARSRC1_0960
MalathionJUNATG_AP_1_CIS_up
MalathionSMAD1ATG_BRE_CIS_up
MalathionMTF1ATG_MRE_CIS_up
MalathionNFE2L2TOX21_ARE_BLA_agonist_ratio
MalathionNFE2L2ATG_NRF2_ARE_CIS_up
MalathionNR4A2ATG_NURR1_TRANS_up
MalathionPAX6ATG_Pax6_CIS_up
MalathionLEF1ATG_TCF_b_cat_CIS_dn
MalathionPGRCEETOX_H295R_PROG_up
MalathionPGRCEETOX_H295R_OHPROG_up
MalathionPLAURBSK_3C_uPAR_down
MalathionPOU2F1ATG_Oct_MLP_CIS_up
MalathionPPARAATG_PPRE_CIS_up
MalathionPPARDATG_PPRE_CIS_up
MalathionPPARGATG_PPRE_CIS_up
MalathionPPARGATG_PPARg_TRANS_up
MalathionPPP1CANVS_ENZ_hPPP1CA
MalathionRORAATG_RORE_CIS_up
MalathionRORBATG_RORE_CIS_up
MalathionRORCATG_RORE_CIS_up
MalathionRXRBATG_RXRb_TRANS_up
MalathionSELEBSK_3C_Eselectin_down
MalathionTCF7ATG_TCF_b_cat_CIS_dn
MalathionTCF7L2ATG_TCF_b_cat_CIS_dn
MalathionTFAP2AATG_AP_2_CIS_dn
MalathionTFAP2BATG_AP_2_CIS_dn
MalathionTSPONVS_MP_hPBR
MalathionNR1H2ATG_LXRb_TRANS_up
MalathionVDRATG_VDRE_CIS_up
MalathionXBP1ATG_Xbp1_CIS_up
MalathionTCF7L1ATG_TCF_b_cat_CIS_dn
MalathionTFAP2DATG_AP_2_CIS_dn
MalathionNR1I2ATG_PXR_TRANS_up
MalathionNR1I2ATG_PXRE_CIS_up
MalathionNR1I3TOX21_CAR_Agonist
MalathionNR1I3NVS_NR_hCAR_Antagonist
MalathionNR1H4ATG_FXR_TRANS_up

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