Fenarimol

Target genes for Fenarimol is obtained based on ToxCast assay component endpoints.
Chemical nameGene identifierToxCast assay component endpoint name
FenarimolNR1H3ATG_DR4_LXR_CIS_dn
FenarimolNACEETOX_H295R_PROG_noMTC_dn
FenarimolESR1CEETOX_H295R_TESTO_noMTC_dn
FenarimolESR1CEETOX_H295R_ESTRONE_noMTC_dn
FenarimolESR1CEETOX_H295R_ESTRADIOL_noMTC_dn
FenarimolNACEETOX_H295R_ANDR_noMTC_dn
FenarimolNACEETOX_H295R_TESTO_noMTC_dn
FenarimolCOL3A1BSK_hDFCGF_CollagenIII_down
FenarimolADORA1NVS_GPCR_hAdoRA1
FenarimolCSF1BSK_LPS_MCSF_down
FenarimolCYP1A1NVS_ADME_hCYP1A1
FenarimolCYP2A6NVS_ADME_hCYP2A6
FenarimolCYP2B6NVS_ADME_hCYP2B6
FenarimolCYP2B6CLD_CYP2B6_24hr
FenarimolCYP2B6CLD_CYP2B6_48hr
FenarimolCYP2B6CLD_CYP2B6_6hr
FenarimolCYP2C19NVS_ADME_hCYP2C19
FenarimolCYP2C8NVS_ADME_hCYP2C8
FenarimolCYP2C9NVS_ADME_hCYP2C9
FenarimolCYP2C18NVS_ADME_hCYP2C18
FenarimolCYP2J2NVS_ADME_hCYP2J2
FenarimolCYP3A4CLD_CYP3A4_24hr
FenarimolCYP3A4NVS_ADME_hCYP3A4
FenarimolCYP3A4CLD_CYP3A4_48hr
FenarimolCYP19A1TOX21_Aromatase_Inhibition
FenarimolEGR1ATG_EGR_CIS_up
FenarimolESR1TOX21_ERa_LUC_VM7_Antagonist_0.1nM_E2
FenarimolESR1OT_ERa_EREGFP_0480
FenarimolESR1TOX21_ERa_BLA_Antagonist_ratio
FenarimolESR1OT_ER_ERaERb_0480
FenarimolESR1OT_ER_ERaERb_1440
FenarimolESR1TOX21_ERa_BLA_Agonist_ratio
FenarimolESR1ATG_ERa_TRANS_up
FenarimolESR1TOX21_ERa_LUC_VM7_Agonist
FenarimolESR1CEETOX_H295R_TESTO_noMTC_dn
FenarimolESR1CEETOX_H295R_ESTRONE_noMTC_dn
FenarimolESR1CEETOX_H295R_ESTRADIOL_noMTC_dn
FenarimolESR1ATG_ERE_CIS_up
FenarimolESR2OT_ER_ERbERb_1440
FenarimolESR2OT_ER_ERaERb_0480
FenarimolESR2CEETOX_H295R_ESTRONE_noMTC_dn
FenarimolESR2OT_ER_ERbERb_0480
FenarimolESR2TOX21_ERb_BLA_Antagonist_ratio
FenarimolESR2CEETOX_H295R_ESTRADIOL_noMTC_dn
FenarimolESR2CEETOX_H295R_TESTO_noMTC_dn
FenarimolESR2OT_ER_ERaERb_1440
FenarimolESRRATOX21_ERR_Antagonist
FenarimolETS1ATG_Ets_CIS_dn
FenarimolFOSATG_AP_1_CIS_up
FenarimolGATA1ATG_GATA_CIS_dn
FenarimolNR3C1CEETOX_H295R_CORTIC_noMTC_dn
FenarimolNR3C1TOX21_GR_BLA_Antagonist_ratio
FenarimolNR3C1CEETOX_H295R_DOC_noMTC_dn
FenarimolNR3C1ATG_GRE_CIS_dn
FenarimolNR3C1NVS_NR_hGR
FenarimolNR3C1CEETOX_H295R_11DCORT_noMTC_dn
FenarimolNR3C1CEETOX_H295R_CORTISOL_noMTC_dn
FenarimolGSTA2CLD_GSTA2_48hr
FenarimolHIF1AATG_HIF1a_CIS_up
FenarimolHLA-DRABSK_3C_HLADR_down
FenarimolHLA-DRABSK_BE3C_HLADR_down
FenarimolHLA-DRABSK_CASM3C_HLADR_up
FenarimolHSF1ATG_HSE_CIS_up
FenarimolHTR6NVS_GPCR_h5HT6
FenarimolCXCL8BSK_SAg_IL8_down
FenarimolCXCL10BSK_BE3C_IP10_down
FenarimolCXCL10BSK_KF3CT_IP10_down
FenarimolAROT_AR_ARSRC1_0960
FenarimolARACEA_AR_antagonist_80hr
FenarimolARCEETOX_H295R_ANDR_noMTC_dn
FenarimolARCEETOX_H295R_TESTO_noMTC_dn
FenarimolARTOX21_AR_LUC_MDAKB2_Antagonist_10nM_R1881
FenarimolARTOX21_AR_LUC_MDAKB2_Antagonist_0.5nM_R1881
FenarimolARTOX21_AR_BLA_Antagonist_ratio
FenarimolJUNATG_AP_1_CIS_up
FenarimolESR1CEETOX_H295R_TESTO_noMTC_dn
FenarimolESR1CEETOX_H295R_ESTRONE_noMTC_dn
FenarimolESR1CEETOX_H295R_ESTRADIOL_noMTC_dn
FenarimolNACEETOX_H295R_TESTO_noMTC_dn
FenarimolNACEETOX_H295R_ESTRONE_noMTC_dn
FenarimolNACEETOX_H295R_ESTRADIOL_noMTC_dn
FenarimolSMAD1ATG_BRE_CIS_up
FenarimolARCEETOX_H295R_ANDR_noMTC_dn
FenarimolARCEETOX_H295R_TESTO_noMTC_dn
FenarimolCXCL9BSK_SAg_MIG_down
FenarimolNR3C2CEETOX_H295R_CORTIC_noMTC_dn
FenarimolNR3C2CEETOX_H295R_DOC_noMTC_dn
FenarimolNR3C2CEETOX_H295R_11DCORT_noMTC_dn
FenarimolNR3C2CEETOX_H295R_CORTISOL_noMTC_dn
FenarimolMMP1BSK_hDFCGF_MMP1_up
FenarimolMTF1ATG_MRE_CIS_up
FenarimolMYCATG_Myc_CIS_up
FenarimolNFE2L2TOX21_ARE_BLA_agonist_ratio
FenarimolNFE2L2ATG_NRF2_ARE_CIS_up
FenarimolOPRD1NVS_GPCR_hOpiate_D1
FenarimolSERPINE1BSK_hDFCGF_PAI1_down
FenarimolPAX6ATG_Pax6_CIS_up
FenarimolPGRCEETOX_H295R_PROG_noMTC_dn
FenarimolPGRTOX21_PR_BLA_Antagonist_ratio
FenarimolABCB1CLD_ABCB1_24hr
FenarimolABCB1CLD_ABCB1_48hr
FenarimolPLAURBSK_3C_uPAR_down
FenarimolPLAURBSK_4H_uPAR_down
FenarimolPOU2F1ATG_Oct_MLP_CIS_up
FenarimolPPARGATG_PPARg_TRANS_up
FenarimolPPARGTOX21_PPARg_BLA_antagonist_ratio
FenarimolPTGER2BSK_LPS_PGE2_up
FenarimolRARAATG_DR5_CIS_up
FenarimolRARBATG_DR5_CIS_up
FenarimolRARGATG_DR5_CIS_up
FenarimolRORAATG_RORE_CIS_up
FenarimolRORBATG_RORE_CIS_up
FenarimolRORCATG_RORE_CIS_up
FenarimolCCL2BSK_4H_MCP1_down
FenarimolCCL2BSK_SAg_MCP1_down
FenarimolSELEBSK_SAg_Eselectin_down
FenarimolSELPBSK_4H_Pselectin_down
FenarimolSLC5A5NIS_RAIU_inhibition
FenarimolSLC6A3NVS_TR_hDAT
FenarimolSP1ATG_Sp1_CIS_up
FenarimolSREBF1ATG_SREBP_CIS_up
FenarimolTHBDBSK_CASM3C_Thrombomodulin_up
FenarimolTNFBSK_LPS_TNFa_up
FenarimolTP53TOX21_p53_BLA_p4_ratio
FenarimolTP53TOX21_p53_BLA_p2_ratio
FenarimolTSHRTOX21_TSHR_Agonist_ratio
FenarimolNR1H2ATG_DR4_LXR_CIS_dn
FenarimolUSF1ATG_E_Box_CIS_dn
FenarimolVDRATG_VDRE_CIS_up
FenarimolNACEETOX_H295R_ANDR_noMTC_dn
FenarimolNACEETOX_H295R_TESTO_noMTC_dn
FenarimolXBP1ATG_Xbp1_CIS_up
FenarimolNR1I2CEETOX_H295R_OHPROG_noMTC_dn
FenarimolNR1I2CEETOX_H295R_OHPREG_noMTC_dn
FenarimolNR1I2ATG_PXRE_CIS_up
FenarimolNR1I2ATG_PXR_TRANS_up
FenarimolABCG2CLD_ABCG2_48hr
FenarimolCD38BSK_SAg_CD38_down
FenarimolCD40BSK_SAg_CD40_down
FenarimolCD40BSK_LPS_CD40_down
FenarimolCD69BSK_SAg_CD69_down
FenarimolNR1I3ATG_PBREM_CIS_up
FenarimolNR1I3NVS_NR_hCAR_Antagonist
FenarimolNR1I3TOX21_CAR_Agonist
FenarimolNR1H4OT_FXR_FXRSRC1_0480
FenarimolNR1H4TOX21_FXR_BLA_antagonist_ratio
FenarimolNR1H4OT_FXR_FXRSRC1_1440

DISCLAIMER

We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.