Hydroxytamoxifen

Target genes for Hydroxytamoxifen is obtained based on ToxCast assay component endpoints.
Chemical nameGene identifierToxCast assay component endpoint name
HydroxytamoxifenCYP19A1TOX21_Aromatase_Inhibition
HydroxytamoxifenCYP24A1TOX21_VDR_BLA_antagonist_ratio
HydroxytamoxifenCYP24A1TOX21_VDR_BLA_agonist_ratio
HydroxytamoxifenESR1TOX21_ERa_BLA_Antagonist_ratio
HydroxytamoxifenESR1TOX21_ERa_LUC_VM7_Antagonist_0.5nM_E2
HydroxytamoxifenESR1TOX21_ERa_BLA_Agonist_ratio
HydroxytamoxifenESR1TOX21_ERa_LUC_VM7_Antagonist_0.1nM_E2
HydroxytamoxifenESR2TOX21_ERb_BLA_Agonist_ratio
HydroxytamoxifenESR2TOX21_ERb_BLA_Antagonist_ratio
HydroxytamoxifenESRRATOX21_ERR_Antagonist
HydroxytamoxifenESRRATOX21_PGC_ERR_Antagonist
HydroxytamoxifenATF6TOX21_ESRE_BLA_ratio
HydroxytamoxifenNR3C1TOX21_GR_BLA_Antagonist_ratio
HydroxytamoxifenNR3C1TOX21_GR_BLA_Agonist_ratio
HydroxytamoxifenHIF1ATOX21_HRE_BLA_Agonist_ratio
HydroxytamoxifenHSF1TOX21_HSE_BLA_agonist_ratio
HydroxytamoxifenARTOX21_AR_BLA_Antagonist_ratio
HydroxytamoxifenARTOX21_AR_LUC_MDAKB2_Antagonist_0.5nM_R1881
HydroxytamoxifenARTOX21_AR_BLA_Agonist_ratio
HydroxytamoxifenJUNTOX21_AP1_BLA_Agonist_ratio
HydroxytamoxifenFOSTOX21_AP1_BLA_Agonist_ratio
HydroxytamoxifenNFKB1TOX21_NFkB_BLA_agonist_ratio
HydroxytamoxifenPGRTOX21_PR_BLA_Antagonist_ratio
HydroxytamoxifenPGRTOX21_PR_BLA_Agonist_ratio
HydroxytamoxifenPPARDTOX21_PPARd_BLA_agonist_ratio
HydroxytamoxifenPPARDTOX21_PPARd_BLA_antagonist_ratio
HydroxytamoxifenPPARGTOX21_PPARg_BLA_Agonist_ratio
HydroxytamoxifenTP53TOX21_p53_BLA_p1_ratio
HydroxytamoxifenTP53TOX21_p53_BLA_p3_ratio
HydroxytamoxifenTP53TOX21_p53_BLA_p4_ratio
HydroxytamoxifenTP53TOX21_p53_BLA_p5_ratio
HydroxytamoxifenTP53TOX21_p53_BLA_p2_ratio
HydroxytamoxifenTSHRTOX21_TSHR_Agonist_ratio
HydroxytamoxifenTSHRTOX21_TSHR_Antagonist_ratio
HydroxytamoxifenVDRTOX21_VDR_BLA_agonist_ratio
HydroxytamoxifenVDRTOX21_VDR_BLA_antagonist_ratio
HydroxytamoxifenNR1I3TOX21_CAR_Antagonist
HydroxytamoxifenNR1H4TOX21_FXR_BLA_antagonist_ratio
HydroxytamoxifenNR1H4TOX21_FXR_BLA_agonist_ratio

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