Phenothrin

Target genes for Phenothrin is obtained based on ToxCast assay component endpoints.
Chemical nameGene identifierToxCast assay component endpoint name
PhenothrinNR1H3ATG_DR4_LXR_CIS_dn
PhenothrinNACEETOX_H295R_PROG_dn
PhenothrinNACEETOX_H295R_ANDR_dn
PhenothrinCOL3A1BSK_hDFCGF_CollagenIII_down
PhenothrinCSF1BSK_hDFCGF_MCSF_down
PhenothrinESR1ATG_ERa_TRANS_up
PhenothrinESR1ATG_ERE_CIS_up
PhenothrinF3BSK_CASM3C_TissueFactor_down
PhenothrinNR3C1CEETOX_H295R_11DCORT_dn
PhenothrinHLA-DRABSK_CASM3C_HLADR_down
PhenothrinHLA-DRABSK_3C_HLADR_down
PhenothrinCXCL8BSK_LPS_IL8_down
PhenothrinARACEA_AR_agonist_80hr
PhenothrinAROT_AR_ARSRC1_0960
PhenothrinARCEETOX_H295R_ANDR_dn
PhenothrinARCEETOX_H295R_ANDR_dn
PhenothrinNR3C2CEETOX_H295R_11DCORT_dn
PhenothrinMMP9NVS_ENZ_hMMP9
PhenothrinNFE2L2ATG_NRF2_ARE_CIS_up
PhenothrinNR4A2ATG_NURR1_TRANS_dn
PhenothrinSERPINE1BSK_hDFCGF_PAI1_down
PhenothrinSERPINE1BSK_BE3C_PAI1_up
PhenothrinPGRCEETOX_H295R_OHPREG_dn
PhenothrinPGRTOX21_PR_BLA_Antagonist_ratio
PhenothrinPGRCEETOX_H295R_PROG_dn
PhenothrinPGRCEETOX_H295R_OHPROG_dn
PhenothrinPLATBSK_BE3C_tPA_down
PhenothrinPPARGATG_PPARg_TRANS_up
PhenothrinCCL2BSK_4H_MCP1_down
PhenothrinSELEBSK_3C_Eselectin_down
PhenothrinSELEBSK_SAg_Eselectin_down
PhenothrinSLC6A3NVS_TR_hDAT
PhenothrinTHBDBSK_CASM3C_Thrombomodulin_up
PhenothrinTIMP1BSK_hDFCGF_TIMP1_down
PhenothrinTIMP2BSK_KF3CT_TIMP2_down
PhenothrinNR1H2ATG_DR4_LXR_CIS_dn
PhenothrinVCAM1BSK_hDFCGF_VCAM1_down
PhenothrinNACEETOX_H295R_ANDR_dn
PhenothrinNR1I2ATG_PXRE_CIS_up
PhenothrinNR1I2ATG_PXR_TRANS_up
PhenothrinNR1I3TOX21_CAR_Agonist
PhenothrinNR1H4OT_FXR_FXRSRC1_1440
PhenothrinNR1H4TOX21_FXR_BLA_antagonist_ratio

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We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.