Colforsin

Target genes for Colforsin is obtained based on ToxCast assay component endpoints.
Chemical nameGene identifierToxCast assay component endpoint name
ColforsinNR1H3ATG_DR4_LXR_CIS_up
ColforsinESR1CEETOX_H295R_ESTRONE_up
ColforsinESR1CEETOX_H295R_ESTRADIOL_up
ColforsinESR1CEETOX_H295R_TESTO_up
ColforsinNACEETOX_H295R_ANDR_up
ColforsinNACEETOX_H295R_TESTO_up
ColforsinCREB3ATG_CRE_CIS_up
ColforsinCYP19A1TOX21_Aromatase_Inhibition
ColforsinESR1TOX21_ERa_LUC_VM7_Antagonist_0.5nM_E2
ColforsinESR1CEETOX_H295R_ESTRADIOL_up
ColforsinESR1TOX21_ERa_LUC_VM7_Antagonist_0.1nM_E2
ColforsinESR1ACEA_ER_80hr
ColforsinESR1CEETOX_H295R_ESTRONE_up
ColforsinESR1OT_ER_ERaERb_1440
ColforsinESR1OT_ERa_EREGFP_0480
ColforsinESR1ATG_ERE_CIS_up
ColforsinESR1ATG_ERa_TRANS_up
ColforsinESR1TOX21_ERa_LUC_VM7_Agonist
ColforsinESR2CEETOX_H295R_ESTRONE_up
ColforsinESR2OT_ER_ERaERb_1440
ColforsinESR2CEETOX_H295R_ESTRADIOL_up
ColforsinESR2OT_ER_ERbERb_1440
ColforsinESR2TOX21_ERb_BLA_Antagonist_ratio
ColforsinESRRATOX21_PGC_ERR_Agonist
ColforsinESRRATOX21_ERR_Agonist
ColforsinNR3C1CEETOX_H295R_11DCORT_up
ColforsinNR3C1CEETOX_H295R_CORTIC_up
ColforsinNR3C1ATG_GR_TRANS_up
ColforsinNR3C1CEETOX_H295R_DOC_up
ColforsinNR3C1CEETOX_H295R_CORTISOL_up
ColforsinARCEETOX_H295R_TESTO_up
ColforsinARTOX21_AR_LUC_MDAKB2_Antagonist_0.5nM_R1881
ColforsinARACEA_AR_antagonist_80hr
ColforsinARCEETOX_H295R_ANDR_up
ColforsinARTOX21_AR_LUC_MDAKB2_Antagonist_10nM_R1881
ColforsinESR1CEETOX_H295R_ESTRADIOL_up
ColforsinESR1CEETOX_H295R_ESTRONE_up
ColforsinESR1CEETOX_H295R_TESTO_up
ColforsinNACEETOX_H295R_ESTRADIOL_up
ColforsinNACEETOX_H295R_TESTO_up
ColforsinNACEETOX_H295R_ESTRONE_up
ColforsinARCEETOX_H295R_TESTO_up
ColforsinARCEETOX_H295R_ANDR_up
ColforsinNR3C2CEETOX_H295R_11DCORT_up
ColforsinNR3C2CEETOX_H295R_CORTIC_up
ColforsinNR3C2CEETOX_H295R_DOC_up
ColforsinNR3C2CEETOX_H295R_CORTISOL_up
ColforsinNFE2L2ATG_NRF2_ARE_CIS_dn
ColforsinNFKB1ATG_NF_kB_CIS_dn
ColforsinPGRCEETOX_H295R_OHPROG_up
ColforsinPGRCEETOX_H295R_OHPREG_up
ColforsinPPARAATG_PPARa_TRANS_up
ColforsinPPARGATG_PPARg_TRANS_up
ColforsinRARAATG_DR5_CIS_up
ColforsinRARBATG_DR5_CIS_up
ColforsinRARGATG_DR5_CIS_up
ColforsinRXRAOT_NURR1_NURR1RXRa_0480
ColforsinRXRAOT_NURR1_NURR1RXRa_1440
ColforsinRXRAATG_RXRa_TRANS_up
ColforsinRXRBATG_RXRb_TRANS_up
ColforsinTHRAATG_THRa1_TRANS_up
ColforsinTP53ATG_p53_CIS_dn
ColforsinTSHRTOX21_TSHR_wt_ratio
ColforsinTSHRTOX21_TSHR_Agonist_ratio
ColforsinNR1H2ATG_LXRb_TRANS_up
ColforsinNR1H2ATG_DR4_LXR_CIS_up
ColforsinVDRATG_VDRE_CIS_up
ColforsinNACEETOX_H295R_TESTO_up
ColforsinNACEETOX_H295R_ANDR_up
ColforsinNR1I2ATG_PXR_TRANS_up
ColforsinNR1I2ATG_PXRE_CIS_up
ColforsinNR1I3ATG_PBREM_CIS_up
ColforsinNR1I3TOX21_CAR_Antagonist
ColforsinNR1H4ATG_IR1_CIS_up
ColforsinNR1H4OT_FXR_FXRSRC1_0480
ColforsinNR1H4ATG_FXR_TRANS_up
ColforsinNR1H4OT_FXR_FXRSRC1_1440

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