Prometryn

Target genes for Prometryn is obtained based on ToxCast assay component endpoints.
Chemical nameGene identifierToxCast assay component endpoint name
PrometrynESR1CEETOX_H295R_ESTRONE_up
PrometrynCREB3ATG_CRE_CIS_up
PrometrynADORA1NVS_GPCR_hAdoRA1
PrometrynADORA2ANVS_GPCR_hAdoRA2a
PrometrynCSF1BSK_LPS_MCSF_down
PrometrynCYP1A1NVS_ADME_hCYP1A1
PrometrynCYP1A1CLD_CYP1A1_48hr
PrometrynCYP1A1CLD_CYP1A1_6hr
PrometrynCYP1A1CLD_CYP1A1_24hr
PrometrynCYP1A2CLD_CYP1A2_24hr
PrometrynCYP1A2NVS_ADME_hCYP1A2
PrometrynCYP1A2CLD_CYP1A2_48hr
PrometrynCYP2B6CLD_CYP2B6_48hr
PrometrynCYP2B6CLD_CYP2B6_6hr
PrometrynCYP2B6CLD_CYP2B6_24hr
PrometrynCYP2C19NVS_ADME_hCYP2C19
PrometrynCYP2J2NVS_ADME_hCYP2J2
PrometrynCYP3A4CLD_CYP3A4_48hr
PrometrynCYP3A4CLD_CYP3A4_24hr
PrometrynESR1TOX21_ERa_BLA_Antagonist_ratio
PrometrynESR1CEETOX_H295R_ESTRONE_up
PrometrynESR2TOX21_ERb_BLA_Antagonist_ratio
PrometrynESR2CEETOX_H295R_ESTRONE_up
PrometrynKCNH2NVS_IC_hKhERGCh
PrometrynESR1CEETOX_H295R_ESTRONE_up
PrometrynNACEETOX_H295R_ESTRONE_up
PrometrynNFE2L2TOX21_ARE_BLA_agonist_ratio
PrometrynNFE2L2ATG_NRF2_ARE_CIS_up
PrometrynPDE4ANVS_ENZ_hPDE4A1
PrometrynPGRTOX21_PR_BLA_Antagonist_ratio
PrometrynPOU2F1ATG_Oct_MLP_CIS_up
PrometrynPPARAATG_PPRE_CIS_up
PrometrynPPARDATG_PPRE_CIS_up
PrometrynPPARGATG_PPRE_CIS_up
PrometrynPPARGATG_PPARg_TRANS_up
PrometrynRARAATG_RARa_TRANS_up
PrometrynRARAATG_DR5_CIS_up
PrometrynRARBATG_DR5_CIS_up
PrometrynRARGATG_DR5_CIS_up
PrometrynCCL2BSK_SAg_MCP1_down
PrometrynSLC5A5NIS_RAIU_inhibition
PrometrynTNFBSK_LPS_TNFa_down
PrometrynVDRATG_VDRE_CIS_up
PrometrynPDE5ANVS_ENZ_hPDE5
PrometrynNR1I2ATG_PXRE_CIS_up
PrometrynNR1I2ATG_PXR_TRANS_up
PrometrynNR1I3ATG_PBREM_CIS_up
PrometrynNR1I3TOX21_CAR_Agonist

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