Biochanin A

Target genes for Biochanin A is obtained based on ToxCast assay component endpoints.
Chemical nameGene identifierToxCast assay component endpoint name
Biochanin ANR1H3ATG_DR4_LXR_CIS_dn
Biochanin ANACEETOX_H295R_PROG_dn
Biochanin AESR1CEETOX_H295R_TESTO_dn
Biochanin ANACEETOX_H295R_ANDR_dn
Biochanin ANACEETOX_H295R_TESTO_dn
Biochanin AAHRATG_Ahr_CIS_up
Biochanin AAHRTOX21_AhR_LUC_Agonist
Biochanin AESR1OT_ER_ERaERa_0480
Biochanin AESR1OT_ER_ERaERb_0480
Biochanin AESR1TOX21_ERa_BLA_Antagonist_ratio
Biochanin AESR1ATG_ERE_CIS_up
Biochanin AESR1ACEA_ER_80hr
Biochanin AESR1OT_ERa_EREGFP_0120
Biochanin AESR1NVS_NR_hER
Biochanin AESR1ATG_ERa_TRANS_up
Biochanin AESR1TOX21_ERa_BLA_Agonist_ratio
Biochanin AESR1TOX21_ERa_LUC_VM7_Agonist
Biochanin AESR1OT_ER_ERaERa_1440
Biochanin AESR1OT_ER_ERaERb_1440
Biochanin AESR1OT_ERa_EREGFP_0480
Biochanin AESR2TOX21_ERb_BLA_Antagonist_ratio
Biochanin AESR2OT_ER_ERaERb_1440
Biochanin AESR2OT_ER_ERbERb_1440
Biochanin AESR2OT_ER_ERaERb_0480
Biochanin AESR2OT_ER_ERbERb_0480
Biochanin AESRRATOX21_ERR_Agonist
Biochanin AESRRATOX21_PGC_ERR_Agonist
Biochanin AATF6TOX21_ESRE_BLA_ratio
Biochanin AFOSATG_AP_1_CIS_up
Biochanin ANR3C1CEETOX_H295R_11DCORT_dn
Biochanin ANR3C1CEETOX_H295R_CORTISOL_dn
Biochanin ANR3C1CEETOX_H295R_DOC_dn
Biochanin AHDAC1TOX21_HDAC_Inhibition
Biochanin AHSF1ATG_HSE_CIS_up
Biochanin AARCEETOX_H295R_TESTO_dn
Biochanin AARCEETOX_H295R_ANDR_dn
Biochanin AARACEA_AR_antagonist_80hr
Biochanin AARTOX21_AR_BLA_Antagonist_ratio
Biochanin AJUNATG_AP_1_CIS_up
Biochanin AESR1CEETOX_H295R_TESTO_dn
Biochanin ANACEETOX_H295R_TESTO_dn
Biochanin ASMAD1ATG_BRE_CIS_up
Biochanin AARCEETOX_H295R_ANDR_dn
Biochanin AARCEETOX_H295R_TESTO_dn
Biochanin ANR3C2CEETOX_H295R_11DCORT_dn
Biochanin ANR3C2CEETOX_H295R_DOC_dn
Biochanin ANR3C2CEETOX_H295R_CORTISOL_dn
Biochanin AMTF1ATG_MRE_CIS_up
Biochanin ANFE2L2TOX21_ARE_BLA_agonist_ratio
Biochanin ANFE2L2ATG_NRF2_ARE_CIS_up
Biochanin ANFKB1ATG_NF_kB_CIS_up
Biochanin ANRF1ATG_NRF1_CIS_dn
Biochanin APGRCEETOX_H295R_OHPREG_up
Biochanin APGRTOX21_PR_BLA_Antagonist_ratio
Biochanin APGRCEETOX_H295R_PROG_dn
Biochanin APGRCEETOX_H295R_OHPROG_dn
Biochanin APOU2F1ATG_Oct_MLP_CIS_up
Biochanin APPARAATG_PPARa_TRANS_up
Biochanin APPARAATG_PPRE_CIS_up
Biochanin APPARDTOX21_PPARd_BLA_antagonist_ratio
Biochanin APPARDATG_PPRE_CIS_up
Biochanin APPARGATG_PPARg_TRANS_up
Biochanin APPARGTOX21_PPARg_BLA_antagonist_ratio
Biochanin APPARGATG_PPRE_CIS_up
Biochanin ARORAATG_RORE_CIS_up
Biochanin ARORBATG_RORE_CIS_up
Biochanin ARORCATG_RORE_CIS_up
Biochanin ATSPONVS_MP_hPBR
Biochanin ATP53ATG_p53_CIS_up
Biochanin ATP53TOX21_p53_BLA_p2_ratio
Biochanin ATP53TOX21_p53_BLA_p3_ratio
Biochanin ANR1H2ATG_DR4_LXR_CIS_dn
Biochanin AVDRATG_VDRE_CIS_up
Biochanin ANACEETOX_H295R_TESTO_dn
Biochanin ANACEETOX_H295R_ANDR_dn
Biochanin AXBP1ATG_Xbp1_CIS_up
Biochanin AATAD5TOX21_ELG1_LUC_Agonist
Biochanin ANR1I2ATG_PXR_TRANS_up
Biochanin ANR1I2ATG_PXRE_CIS_up
Biochanin ANR1I3TOX21_CAR_Agonist
Biochanin ANR1H4TOX21_FXR_BLA_antagonist_ratio
Biochanin ANR1H4OT_FXR_FXRSRC1_1440

DISCLAIMER

We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.