Oxytetracycline

Target genes for Oxytetracycline is obtained based on ToxCast assay component endpoints.
Chemical nameGene identifierToxCast assay component endpoint name
OxytetracyclinePAK4NVS_ENZ_hPAK4
OxytetracyclineCCL26BSK_4H_Eotaxin3_down
OxytetracyclineCSF1BSK_hDFCGF_MCSF_down
OxytetracyclineDIO1NHEERL_MED_hDIO1_dn
OxytetracyclineDUSP3NVS_ENZ_hDUSP3
OxytetracyclineAHRATG_Ahr_CIS_up
OxytetracyclineEPHA2NVS_ENZ_hEphA2
OxytetracyclineF3BSK_3C_TissueFactor_up
OxytetracyclineFGFR1NVS_ENZ_hFGFR1
OxytetracyclineFLT1NVS_ENZ_hVEGFR1
OxytetracyclineFLT4NVS_ENZ_hVEGFR3
OxytetracyclineBACE1NVS_ENZ_hBACE
OxytetracyclineNR3C1NVS_NR_hGR
OxytetracyclineIL1ABSK_KF3CT_IL1a_down
OxytetracyclineCXCL8BSK_LPS_IL8_down
OxytetracyclineCXCL10BSK_hDFCGF_IP10_down
OxytetracyclineARACEA_AR_antagonist_80hr
OxytetracyclineJUNTOX21_AP1_BLA_Agonist_ratio
OxytetracyclineKDRNVS_ENZ_hVEGFR2
OxytetracyclineFOSTOX21_AP1_BLA_Agonist_ratio
OxytetracyclineSMAD1ATG_BRE_CIS_dn
OxytetracyclineCXCL9BSK_hDFCGF_MIG_down
OxytetracyclineNFE2L2TOX21_ARE_BLA_agonist_ratio
OxytetracyclineNFE2L2ATG_NRF2_ARE_CIS_up
OxytetracyclineSERPINE1BSK_BE3C_PAI1_up
OxytetracyclinePIK3CANVS_ENZ_hPI3Ka
OxytetracyclinePPARANVS_NR_hPPARa
OxytetracyclinePPARGNVS_NR_hPPARg
OxytetracyclineMAPK3NVS_ENZ_hMAPK3
OxytetracyclinePTENNVS_ENZ_hPTEN
OxytetracyclinePTPN11NVS_ENZ_hPTPN11
OxytetracyclinePTPN12NVS_ENZ_hPTPN12
OxytetracyclinePTPRBNVS_ENZ_hPTPRB
OxytetracyclineRARANVS_NR_hRARa_Agonist
OxytetracyclineRARANVS_NR_hRAR_Antagonist
OxytetracyclineRXRAOT_NURR1_NURR1RXRa_0480
OxytetracyclineRXRAOT_NURR1_NURR1RXRa_1440
OxytetracyclineTEKNVS_ENZ_hTie2
OxytetracyclineTSPONVS_MP_hPBR
OxytetracyclineTHRANVS_NR_hTRa_Antagonist
OxytetracyclineVCAM1BSK_hDFCGF_VCAM1_down
OxytetracyclineCASP5NVS_ENZ_hCASP5
OxytetracyclineCASP8NVS_ENZ_hCASP8
OxytetracyclineNR1I2NVS_NR_hPXR
OxytetracyclineNR1I2ATG_PXRE_CIS_up
OxytetracyclineNR1H4NVS_NR_hFXR_Agonist

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We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.

NR1H4