Trichlorfon

Target genes for Trichlorfon is obtained based on ToxCast assay component endpoints.
Chemical nameGene identifierToxCast assay component endpoint name
TrichlorfonNR1H3ATG_LXRa_TRANS_up
TrichlorfonCREB3ATG_CRE_CIS_up
TrichlorfonCEBPBATG_C_EBP_CIS_up
TrichlorfonEGR1ATG_EGR_CIS_up
TrichlorfonESR1OT_ER_ERaERb_0480
TrichlorfonESR1ATG_ERa_TRANS_up
TrichlorfonESR1OT_ER_ERaERb_1440
TrichlorfonESR1TOX21_ERa_LUC_VM7_Agonist
TrichlorfonESR1OT_ERa_EREGFP_0480
TrichlorfonESR2OT_ER_ERbERb_1440
TrichlorfonESR2OT_ER_ERaERb_1440
TrichlorfonESR2OT_ER_ERbERb_0480
TrichlorfonESR2OT_ER_ERaERb_0480
TrichlorfonESRRATOX21_ERR_Antagonist
TrichlorfonETS1ATG_Ets_CIS_dn
TrichlorfonFOSATG_AP_1_CIS_up
TrichlorfonNR3C1ATG_GRE_CIS_dn
TrichlorfonHLA-DRABSK_BE3C_HLADR_up
TrichlorfonHNF4AATG_HNF4a_TRANS_up
TrichlorfonARACEA_AR_antagonist_80hr
TrichlorfonARTOX21_AR_BLA_Agonist_ratio
TrichlorfonJUNATG_AP_1_CIS_up
TrichlorfonSMAD1ATG_BRE_CIS_up
TrichlorfonMTF1ATG_MRE_CIS_up
TrichlorfonMYCATG_Myc_CIS_up
TrichlorfonNFE2L2TOX21_ARE_BLA_agonist_ratio
TrichlorfonNFE2L2ATG_NRF2_ARE_CIS_up
TrichlorfonPGRTOX21_PR_BLA_Antagonist_ratio
TrichlorfonPLAURBSK_BE3C_uPAR_up
TrichlorfonPOU2F1ATG_Oct_MLP_CIS_up
TrichlorfonPPARAATG_PPRE_CIS_up
TrichlorfonUGT1A1CLD_UGT1A1_48hr
TrichlorfonPPARDATG_PPRE_CIS_up
TrichlorfonPPARGATG_PPARg_TRANS_up
TrichlorfonPPARGATG_PPRE_CIS_up
TrichlorfonPTGER2BSK_LPS_PGE2_up
TrichlorfonRARAATG_RARa_TRANS_up
TrichlorfonRORAATG_RORE_CIS_up
TrichlorfonRORBATG_RORE_CIS_up
TrichlorfonRORCATG_RORE_CIS_up
TrichlorfonSELEBSK_SAg_Eselectin_down
TrichlorfonSP1ATG_Sp1_CIS_up
TrichlorfonSREBF1ATG_SREBP_CIS_up
TrichlorfonTHRAATG_THRa1_TRANS_up
TrichlorfonTP53APR_HepG2_p53Act_72h_dn
TrichlorfonTP53ATG_p53_CIS_up
TrichlorfonNR1H2ATG_LXRb_TRANS_up
TrichlorfonVDRATG_VDRE_CIS_up
TrichlorfonVDRATG_VDR_TRANS_up
TrichlorfonXBP1ATG_Xbp1_CIS_up
TrichlorfonNR1I2ATG_PXRE_CIS_up
TrichlorfonNR1H4OT_FXR_FXRSRC1_1440
TrichlorfonNR1H4ATG_FXR_TRANS_up

DISCLAIMER

We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.