Bisphenol B

Target genes for Bisphenol B is obtained based on ToxCast assay component endpoints.
Chemical nameGene identifierToxCast assay component endpoint name
Bisphenol BNR1H3ATG_DR4_LXR_CIS_dn
Bisphenol BCOL3A1BSK_hDFCGF_CollagenIII_down
Bisphenol BADORA1NVS_GPCR_hAdoRA1
Bisphenol BCSF1BSK_LPS_MCSF_down
Bisphenol BCYP2B6NVS_ADME_hCYP2B6
Bisphenol BCYP2C19NVS_ADME_hCYP2C19
Bisphenol BCYP2C9NVS_ADME_hCYP2C9
Bisphenol BCYP19A1TOX21_Aromatase_Inhibition
Bisphenol BDRD1NVS_GPCR_hDRD1
Bisphenol BEGR1ATG_EGR_CIS_up
Bisphenol BESR1TOX21_ERa_LUC_VM7_Agonist
Bisphenol BESR1OT_ER_ERaERb_0480
Bisphenol BESR1OT_ERa_EREGFP_0120
Bisphenol BESR1OT_ERa_EREGFP_0480
Bisphenol BESR1ACEA_ER_80hr
Bisphenol BESR1ATG_ERE_CIS_up
Bisphenol BESR1TOX21_ERa_BLA_Antagonist_ratio
Bisphenol BESR1OT_ER_ERaERa_0480
Bisphenol BESR1ATG_ERa_TRANS_up
Bisphenol BESR1OT_ER_ERaERa_1440
Bisphenol BESR1TOX21_ERa_LUC_VM7_Antagonist_0.5nM_E2
Bisphenol BESR1NVS_NR_hER
Bisphenol BESR1TOX21_ERa_LUC_VM7_Antagonist_0.1nM_E2
Bisphenol BESR1OT_ER_ERaERb_1440
Bisphenol BESR2OT_ER_ERbERb_0480
Bisphenol BESR2OT_ER_ERaERb_1440
Bisphenol BESR2OT_ER_ERbERb_1440
Bisphenol BESR2TOX21_ERb_BLA_Antagonist_ratio
Bisphenol BESR2OT_ER_ERaERb_0480
Bisphenol BESRRATOX21_ERR_Antagonist
Bisphenol BESRRATOX21_PGC_ERR_Antagonist
Bisphenol BETS1ATG_Ets_CIS_dn
Bisphenol BFOSATG_AP_1_CIS_up
Bisphenol BBACE1NVS_ENZ_hBACE
Bisphenol BGATA1ATG_GATA_CIS_dn
Bisphenol BNR3C1TOX21_GR_BLA_Antagonist_ratio
Bisphenol BNR3C1NVS_NR_hGR
Bisphenol BHIF1AATG_HIF1a_CIS_up
Bisphenol BHLA-DRABSK_BE3C_HLADR_down
Bisphenol BHLA-DRABSK_3C_HLADR_down
Bisphenol BHTR5ANVS_GPCR_h5HT5A
Bisphenol BHTR6NVS_GPCR_h5HT6
Bisphenol BHTR7NVS_GPCR_h5HT7
Bisphenol BCXCL8BSK_3C_IL8_down
Bisphenol BCXCL8BSK_SAg_IL8_down
Bisphenol BCXCL10BSK_hDFCGF_IP10_down
Bisphenol BCXCL10BSK_KF3CT_IP10_down
Bisphenol BCXCL10BSK_BE3C_IP10_down
Bisphenol BIRF1ATG_ISRE_CIS_dn
Bisphenol BARTOX21_AR_LUC_MDAKB2_Antagonist_0.5nM_R1881
Bisphenol BARTOX21_AR_LUC_MDAKB2_Antagonist_10nM_R1881
Bisphenol BAROT_AR_ARSRC1_0480
Bisphenol BARNVS_NR_hAR
Bisphenol BARACEA_AR_antagonist_80hr
Bisphenol BARTOX21_AR_BLA_Antagonist_ratio
Bisphenol BAROT_AR_ARSRC1_0960
Bisphenol BJUNTOX21_AP1_BLA_Agonist_ratio
Bisphenol BJUNATG_AP_1_CIS_up
Bisphenol BFOSTOX21_AP1_BLA_Agonist_ratio
Bisphenol BMMP1BSK_BE3C_MMP1_up
Bisphenol BMTF1ATG_MRE_CIS_up
Bisphenol BNFIAATG_NFI_CIS_up
Bisphenol BNFE2L2ATG_NRF2_ARE_CIS_up
Bisphenol BNFE2L2TOX21_ARE_BLA_agonist_ratio
Bisphenol BOPRD1NVS_GPCR_hOpiate_D1
Bisphenol BOPRM1NVS_GPCR_hOpiate_mu
Bisphenol BPAX6ATG_Pax6_CIS_up
Bisphenol BLEF1ATG_TCF_b_cat_CIS_dn
Bisphenol BPGRTOX21_PR_BLA_Antagonist_ratio
Bisphenol BPGRNVS_NR_hPR
Bisphenol BPLAUBSK_BE3C_uPA_up
Bisphenol BPLAURBSK_3C_uPAR_down
Bisphenol BPLAURBSK_4H_uPAR_down
Bisphenol BPOU2F1ATG_Oct_MLP_CIS_up
Bisphenol BPPARDTOX21_PPARd_BLA_antagonist_ratio
Bisphenol BPPARGTOX21_PPARg_BLA_antagonist_ratio
Bisphenol BPPARGATG_PPARg_TRANS_up
Bisphenol BPTGER2BSK_LPS_PGE2_down
Bisphenol BPTPN6NVS_ENZ_hPTPN6_Activator
Bisphenol BRORAATG_RORE_CIS_up
Bisphenol BRORBATG_RORE_CIS_up
Bisphenol BRORCATG_RORE_CIS_up
Bisphenol BRXRAOT_NURR1_NURR1RXRa_0480
Bisphenol BRXRBATG_RXRb_TRANS_up
Bisphenol BCCL2BSK_4H_MCP1_down
Bisphenol BCCL2BSK_3C_MCP1_down
Bisphenol BCCL2BSK_SAg_MCP1_down
Bisphenol BSELEBSK_SAg_Eselectin_down
Bisphenol BSELPBSK_4H_Pselectin_down
Bisphenol BSLC5A5NIS_RAIU_inhibition
Bisphenol BSLC6A2NVS_TR_hNET
Bisphenol BSLC6A3NVS_TR_hDAT
Bisphenol BSP1ATG_Sp1_CIS_up
Bisphenol BSREBF1ATG_SREBP_CIS_up
Bisphenol BTCF7ATG_TCF_b_cat_CIS_dn
Bisphenol BTCF7L2ATG_TCF_b_cat_CIS_dn
Bisphenol BTFAP2AATG_AP_2_CIS_dn
Bisphenol BTFAP2BATG_AP_2_CIS_dn
Bisphenol BTHBDBSK_CASM3C_Thrombomodulin_up
Bisphenol BTSPONVS_MP_hPBR
Bisphenol BTP53APR_HepG2_p53Act_24h_up
Bisphenol BTP53ATG_p53_CIS_dn
Bisphenol BTP53TOX21_p53_BLA_p3_ratio
Bisphenol BTP53TOX21_p53_BLA_p5_ratio
Bisphenol BTP53TOX21_p53_BLA_p1_ratio
Bisphenol BTP53TOX21_p53_BLA_p4_ratio
Bisphenol BTP53TOX21_p53_BLA_p2_ratio
Bisphenol BTSHRTOX21_TSHR_Agonist_ratio
Bisphenol BNR1H2ATG_DR4_LXR_CIS_dn
Bisphenol BVCAM1BSK_LPS_VCAM1_down
Bisphenol BVCAM1BSK_hDFCGF_VCAM1_down
Bisphenol BVCAM1BSK_4H_VCAM1_down
Bisphenol BVDRATG_VDRE_CIS_up
Bisphenol BXBP1ATG_Xbp1_CIS_up
Bisphenol BTCF7L1ATG_TCF_b_cat_CIS_dn
Bisphenol BTFAP2DATG_AP_2_CIS_dn
Bisphenol BNR1I2ATG_PXRE_CIS_up
Bisphenol BNR1I2NVS_NR_hPXR
Bisphenol BNR1I2ATG_PXR_TRANS_up
Bisphenol BCD38BSK_SAg_CD38_down
Bisphenol BCD40BSK_LPS_CD40_down
Bisphenol BCD40BSK_SAg_CD40_down
Bisphenol BCD69BSK_SAg_CD69_down
Bisphenol BNR1I3TOX21_CAR_Antagonist
Bisphenol BNR1I3TOX21_CAR_Agonist
Bisphenol BNR1H4ATG_IR1_CIS_dn
Bisphenol BNR1H4OT_FXR_FXRSRC1_1440
Bisphenol BNR1H4TOX21_FXR_BLA_antagonist_ratio

DISCLAIMER

We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.