Perfluoro-n-nonanoic acid

Target genes for Perfluoro-n-nonanoic acid is obtained based on ToxCast assay component endpoints.
Chemical nameGene identifierToxCast assay component endpoint name
Perfluoro-n-nonanoic acidNR1H3ATG_LXRa_TRANS_up
Perfluoro-n-nonanoic acidNR1H3ATG_DR4_LXR_CIS_dn
Perfluoro-n-nonanoic acidADORA2ANVS_GPCR_hAdoRA2a
Perfluoro-n-nonanoic acidADRA2CNVS_GPCR_hAdra2C
Perfluoro-n-nonanoic acidCYP2C9NVS_ADME_hCYP2C9
Perfluoro-n-nonanoic acidE2F1ATG_E2F_CIS_dn
Perfluoro-n-nonanoic acidESR1TOX21_ERa_BLA_Antagonist_ratio
Perfluoro-n-nonanoic acidESR1ATG_ERE_CIS_up
Perfluoro-n-nonanoic acidESR1ATG_ERa_TRANS_up
Perfluoro-n-nonanoic acidESR2TOX21_ERb_BLA_Antagonist_ratio
Perfluoro-n-nonanoic acidESRRATOX21_ERR_Antagonist
Perfluoro-n-nonanoic acidFOSATG_AP_1_CIS_up
Perfluoro-n-nonanoic acidBACE1NVS_ENZ_hBACE
Perfluoro-n-nonanoic acidHLA-DRABSK_BE3C_HLADR_down
Perfluoro-n-nonanoic acidHTR5ANVS_GPCR_h5HT5A
Perfluoro-n-nonanoic acidIL1ABSK_BE3C_IL1a_down
Perfluoro-n-nonanoic acidCXCL8BSK_LPS_IL8_up
Perfluoro-n-nonanoic acidCXCL10BSK_KF3CT_IP10_down
Perfluoro-n-nonanoic acidCXCL10BSK_BE3C_IP10_down
Perfluoro-n-nonanoic acidARNVS_NR_hAR
Perfluoro-n-nonanoic acidARACEA_AR_antagonist_80hr
Perfluoro-n-nonanoic acidJUNATG_AP_1_CIS_up
Perfluoro-n-nonanoic acidCXCL9BSK_BE3C_MIG_down
Perfluoro-n-nonanoic acidMMP9BSK_KF3CT_MMP9_down
Perfluoro-n-nonanoic acidMTF1ATG_MRE_CIS_up
Perfluoro-n-nonanoic acidNEK2NVS_ENZ_hNEK2
Perfluoro-n-nonanoic acidNFE2L2TOX21_ARE_BLA_agonist_ratio
Perfluoro-n-nonanoic acidNFE2L2ATG_NRF2_ARE_CIS_up
Perfluoro-n-nonanoic acidNTRK1NVS_ENZ_hTrkA
Perfluoro-n-nonanoic acidSERPINE1BSK_BE3C_PAI1_down
Perfluoro-n-nonanoic acidLEF1ATG_TCF_b_cat_CIS_dn
Perfluoro-n-nonanoic acidPLATBSK_BE3C_tPA_down
Perfluoro-n-nonanoic acidPLAUBSK_BE3C_uPA_down
Perfluoro-n-nonanoic acidPLAURBSK_BE3C_uPAR_down
Perfluoro-n-nonanoic acidPPARAATG_PPARa_TRANS_up
Perfluoro-n-nonanoic acidPPARAATG_PPRE_CIS_up
Perfluoro-n-nonanoic acidPPARDATG_PPRE_CIS_up
Perfluoro-n-nonanoic acidPPARDTOX21_PPARd_BLA_antagonist_ratio
Perfluoro-n-nonanoic acidPPARGATG_PPARg_TRANS_up
Perfluoro-n-nonanoic acidPPARGTOX21_PPARg_BLA_antagonist_ratio
Perfluoro-n-nonanoic acidPPARGATG_PPRE_CIS_up
Perfluoro-n-nonanoic acidPRKAA1NVS_ENZ_hAMPKa1
Perfluoro-n-nonanoic acidPTGER2BSK_LPS_PGE2_down
Perfluoro-n-nonanoic acidPTPN1NVS_ENZ_hPTPN1_Activator
Perfluoro-n-nonanoic acidPTPN9NVS_ENZ_hPTPN9
Perfluoro-n-nonanoic acidPTPRBNVS_ENZ_hPTPRB
Perfluoro-n-nonanoic acidRARANVS_NR_hRAR_Antagonist
Perfluoro-n-nonanoic acidRXRAATG_RXRa_TRANS_up
Perfluoro-n-nonanoic acidRXRATOX21_RXR_BLA_Agonist_ratio
Perfluoro-n-nonanoic acidRXRBATG_RXRb_TRANS_up
Perfluoro-n-nonanoic acidSP1ATG_Sp1_CIS_up
Perfluoro-n-nonanoic acidAURKANVS_ENZ_hAurA
Perfluoro-n-nonanoic acidTBXA2RNVS_GPCR_hTXA2
Perfluoro-n-nonanoic acidTCF7ATG_TCF_b_cat_CIS_dn
Perfluoro-n-nonanoic acidTCF7L2ATG_TCF_b_cat_CIS_dn
Perfluoro-n-nonanoic acidTEKNVS_ENZ_hTie2
Perfluoro-n-nonanoic acidTGFB1BSK_BE3C_TGFb1_down
Perfluoro-n-nonanoic acidTGFB1ATG_TGFb_CIS_up
Perfluoro-n-nonanoic acidTP53TOX21_p53_BLA_p1_ratio
Perfluoro-n-nonanoic acidTP53APR_HepG2_p53Act_72h_up
Perfluoro-n-nonanoic acidTP53TOX21_p53_BLA_p5_ratio
Perfluoro-n-nonanoic acidTP53APR_HepG2_p53Act_24h_up
Perfluoro-n-nonanoic acidNR1H2ATG_DR4_LXR_CIS_dn
Perfluoro-n-nonanoic acidTCF7L1ATG_TCF_b_cat_CIS_dn
Perfluoro-n-nonanoic acidCASP5NVS_ENZ_hCASP5
Perfluoro-n-nonanoic acidNR1I2ATG_PXRE_CIS_up
Perfluoro-n-nonanoic acidNR1I2ATG_PXR_TRANS_up
Perfluoro-n-nonanoic acidNR1I3NVS_NR_hCAR_Antagonist
Perfluoro-n-nonanoic acidNR1H4ATG_FXR_TRANS_up
Perfluoro-n-nonanoic acidNR1H4NVS_NR_hFXR_Antagonist

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We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.