Dinoseb

Target genes for Dinoseb is obtained based on ToxCast assay component endpoints.
Chemical nameGene identifierToxCast assay component endpoint name
DinosebNR1H3ATG_LXRa_TRANS_up
DinosebCCL26BSK_4H_Eotaxin3_down
DinosebCREB3ATG_CRE_CIS_up
DinosebCEBPBATG_C_EBP_CIS_up
DinosebCSF1BSK_hDFCGF_MCSF_down
DinosebCSF1BSK_LPS_MCSF_down
DinosebCSNK1DNVS_ENZ_hCK1D
DinosebCYP2C19NVS_ADME_hCYP2C19
DinosebCYP19A1TOX21_Aromatase_Inhibition
DinosebEGR1ATG_EGR_CIS_up
DinosebESR1TOX21_ERa_BLA_Antagonist_ratio
DinosebESR1ATG_ERa_TRANS_up
DinosebESR1TOX21_ERa_LUC_VM7_Antagonist_0.5nM_E2
DinosebESR1TOX21_ERa_LUC_VM7_Antagonist_0.1nM_E2
DinosebESR2TOX21_ERb_BLA_Antagonist_ratio
DinosebESRRATOX21_PGC_ERR_Antagonist
DinosebESRRATOX21_ERR_Antagonist
DinosebETS1ATG_Ets_CIS_dn
DinosebFOSATG_AP_1_CIS_up
DinosebHIF1AATG_HIF1a_CIS_up
DinosebHLA-DRABSK_BE3C_HLADR_down
DinosebHLA-DRABSK_CASM3C_HLADR_down
DinosebHLA-DRABSK_3C_HLADR_down
DinosebHSF1ATG_HSE_CIS_up
DinosebIL1ABSK_LPS_IL1a_down
DinosebCXCL8BSK_3C_IL8_down
DinosebCXCL8BSK_SAg_IL8_down
DinosebCXCL8BSK_LPS_IL8_down
DinosebCXCL10BSK_BE3C_IP10_down
DinosebCXCL10BSK_hDFCGF_IP10_down
DinosebIRF1ATG_ISRE_CIS_dn
DinosebARTOX21_AR_LUC_MDAKB2_Antagonist_10nM_R1881
DinosebARACEA_AR_antagonist_80hr
DinosebAROT_AR_ARSRC1_0960
DinosebARTOX21_AR_BLA_Antagonist_ratio
DinosebARTOX21_AR_LUC_MDAKB2_Antagonist_0.5nM_R1881
DinosebJUNATG_AP_1_CIS_up
DinosebKDRBSK_4H_VEGFRII_down
DinosebLDLRBSK_CASM3C_LDLR_down
DinosebSMAD1ATG_BRE_CIS_up
DinosebCXCL9BSK_SAg_MIG_down
DinosebMMP1BSK_BE3C_MMP1_down
DinosebMMP9BSK_KF3CT_MMP9_down
DinosebMTF1ATG_MRE_CIS_up
DinosebMYBATG_Myb_CIS_dn
DinosebNFE2L2TOX21_ARE_BLA_agonist_ratio
DinosebNFE2L2ATG_NRF2_ARE_CIS_up
DinosebSERPINE1BSK_hDFCGF_PAI1_down
DinosebSERPINE1BSK_BE3C_PAI1_down
DinosebPAX6ATG_Pax6_CIS_up
DinosebPGRTOX21_PR_BLA_Antagonist_ratio
DinosebPLATBSK_BE3C_tPA_down
DinosebPLAUBSK_BE3C_uPA_down
DinosebPLAURBSK_CASM3C_uPAR_down
DinosebPLAURBSK_3C_uPAR_down
DinosebPLAURBSK_4H_uPAR_down
DinosebPOU2F1ATG_Oct_MLP_CIS_up
DinosebPPARAATG_PPARa_TRANS_up
DinosebPPARAATG_PPRE_CIS_up
DinosebPPARDTOX21_PPARd_BLA_agonist_ratio
DinosebPPARDATG_PPRE_CIS_up
DinosebPPARGATG_PPARg_TRANS_up
DinosebPPARGTOX21_PPARg_BLA_antagonist_ratio
DinosebPPARGATG_PPRE_CIS_up
DinosebPTGER2BSK_LPS_PGE2_down
DinosebPTPRCNVS_ENZ_hPTPRC
DinosebRARAATG_DR5_CIS_up
DinosebRARBATG_DR5_CIS_up
DinosebRARGATG_DR5_CIS_up
DinosebRORAATG_RORE_CIS_up
DinosebRORBATG_RORE_CIS_up
DinosebRORCATG_RORE_CIS_up
DinosebRXRBATG_RXRb_TRANS_up
DinosebCCL2BSK_SAg_MCP1_down
DinosebCCL2BSK_3C_MCP1_down
DinosebCCL2BSK_4H_MCP1_down
DinosebCCL2BSK_LPS_MCP1_down
DinosebCCL2BSK_KF3CT_MCP1_up
DinosebSELEBSK_LPS_Eselectin_down
DinosebSELEBSK_SAg_Eselectin_down
DinosebSELEBSK_3C_Eselectin_down
DinosebSELPBSK_4H_Pselectin_down
DinosebSLC5A5NIS_RAIU_inhibition
DinosebSOX1ATG_Sox_CIS_up
DinosebSP1ATG_Sp1_CIS_up
DinosebSREBF1ATG_SREBP_CIS_up
DinosebTGFB1BSK_BE3C_TGFb1_down
DinosebTHRAATG_THRa1_TRANS_up
DinosebTP53TOX21_p53_BLA_p3_ratio
DinosebTP53TOX21_p53_BLA_p5_ratio
DinosebTP53TOX21_p53_BLA_p2_ratio
DinosebTP53TOX21_p53_BLA_p4_ratio
DinosebTP53APR_HepG2_p53Act_72h_up
DinosebNR1H2ATG_LXRb_TRANS_up
DinosebVCAM1BSK_3C_VCAM1_down
DinosebVCAM1BSK_LPS_VCAM1_down
DinosebVCAM1BSK_4H_VCAM1_down
DinosebVDRATG_VDRE_CIS_up
DinosebXBP1ATG_Xbp1_CIS_up
DinosebNR1I2ATG_PXR_TRANS_up
DinosebCD38BSK_SAg_CD38_down
DinosebCD40BSK_LPS_CD40_down
DinosebCD40BSK_SAg_CD40_down
DinosebCD69BSK_SAg_CD69_down
DinosebNR1I3ATG_PBREM_CIS_up
DinosebNR1I3TOX21_CAR_Antagonist
DinosebNR1H4TOX21_FXR_BLA_antagonist_ratio

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