Butylphen

Target genes for Butylphen is obtained based on ToxCast assay component endpoints.
Chemical nameGene identifierToxCast assay component endpoint name
ButylphenNR1H3ATG_DR4_LXR_CIS_dn
ButylphenESR1CEETOX_H295R_ESTRADIOL_up
ButylphenESR1CEETOX_H295R_ESTRONE_up
ButylphenCREB3ATG_CRE_CIS_up
ButylphenESR1CEETOX_H295R_ESTRADIOL_up
ButylphenESR1OT_ER_ERaERb_1440
ButylphenESR1OT_ERa_EREGFP_0120
ButylphenESR1OT_ER_ERaERa_1440
ButylphenESR1CEETOX_H295R_ESTRONE_up
ButylphenESR1ATG_ERE_CIS_up
ButylphenESR1ATG_ERa_TRANS_up
ButylphenESR1ACEA_ER_80hr
ButylphenESR1OT_ERa_EREGFP_0480
ButylphenESR1OT_ER_ERaERb_0480
ButylphenESR1OT_ER_ERaERa_0480
ButylphenESR2OT_ER_ERbERb_0480
ButylphenESR2OT_ER_ERaERb_1440
ButylphenESR2OT_ER_ERbERb_1440
ButylphenESR2CEETOX_H295R_ESTRADIOL_up
ButylphenESR2CEETOX_H295R_ESTRONE_up
ButylphenESR2OT_ER_ERaERb_0480
ButylphenFOSATG_AP_1_CIS_up
ButylphenNR3C1CEETOX_H295R_CORTIC_up
ButylphenHIF1AATG_HIF1a_CIS_dn
ButylphenHLA-DRABSK_CASM3C_HLADR_down
ButylphenARACEA_AR_antagonist_80hr
ButylphenJUNTOX21_AP1_BLA_Agonist_ratio
ButylphenJUNATG_AP_1_CIS_up
ButylphenESR1CEETOX_H295R_ESTRADIOL_up
ButylphenESR1CEETOX_H295R_ESTRONE_up
ButylphenFOSTOX21_AP1_BLA_Agonist_ratio
ButylphenNACEETOX_H295R_ESTRONE_up
ButylphenNACEETOX_H295R_ESTRADIOL_up
ButylphenSMAD1ATG_BRE_CIS_up
ButylphenNR3C2CEETOX_H295R_CORTIC_up
ButylphenMTF1ATG_MRE_CIS_up
ButylphenNFIAATG_NFI_CIS_up
ButylphenNFE2L2ATG_NRF2_ARE_CIS_up
ButylphenPAX6ATG_Pax6_CIS_up
ButylphenLEF1ATG_TCF_b_cat_CIS_dn
ButylphenPGRCEETOX_H295R_OHPROG_up
ButylphenPOU2F1ATG_Oct_MLP_CIS_up
ButylphenPPARAATG_PPARa_TRANS_up
ButylphenPTGER2BSK_LPS_PGE2_down
ButylphenRXRBATG_RXRb_TRANS_up
ButylphenSELEBSK_SAg_Eselectin_up
ButylphenSOX1ATG_Sox_CIS_up
ButylphenSP1ATG_Sp1_CIS_up
ButylphenSREBF1ATG_SREBP_CIS_dn
ButylphenTCF7ATG_TCF_b_cat_CIS_dn
ButylphenTCF7L2ATG_TCF_b_cat_CIS_dn
ButylphenTP53ATG_p53_CIS_dn
ButylphenNR1H2ATG_DR4_LXR_CIS_dn
ButylphenVDRATG_VDRE_CIS_up
ButylphenXBP1ATG_Xbp1_CIS_up
ButylphenTCF7L1ATG_TCF_b_cat_CIS_dn
ButylphenNR1I2ATG_PXR_TRANS_up
ButylphenNR1I2ATG_PXRE_CIS_up
ButylphenNR1I3ATG_PBREM_CIS_up

DISCLAIMER

We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.