Perfluorooctane sulfonic acid

Target genes for Perfluorooctane sulfonic acid is obtained based on ToxCast assay component endpoints.
Chemical nameGene identifierToxCast assay component endpoint name
Perfluorooctane sulfonic acidNR1H3ATG_DR4_LXR_CIS_dn
Perfluorooctane sulfonic acidCDK6NVS_ENZ_hCDK6
Perfluorooctane sulfonic acidPAK4NVS_ENZ_hPAK4
Perfluorooctane sulfonic acidCHUKNVS_ENZ_hIKKa
Perfluorooctane sulfonic acidLTB4RNVS_GPCR_hLTB4_BLT1
Perfluorooctane sulfonic acidCOL3A1BSK_hDFCGF_CollagenIII_down
Perfluorooctane sulfonic acidADORA2ANVS_GPCR_hAdoRA2a
Perfluorooctane sulfonic acidCSF1RNVS_ENZ_hCSF1R_Activator
Perfluorooctane sulfonic acidCSF1RNVS_ENZ_hCSF1R
Perfluorooctane sulfonic acidCSNK1A1NVS_ENZ_hCK1a
Perfluorooctane sulfonic acidCSNK1DNVS_ENZ_hCK1D
Perfluorooctane sulfonic acidADRA2CNVS_GPCR_hAdra2C
Perfluorooctane sulfonic acidADRB1NVS_GPCR_hAdrb1
Perfluorooctane sulfonic acidCYP2B6CLD_CYP2B6_24hr
Perfluorooctane sulfonic acidCYP2C19NVS_ADME_hCYP2C19
Perfluorooctane sulfonic acidCYP2C8NVS_ADME_hCYP2C8
Perfluorooctane sulfonic acidCYP2C9NVS_ADME_hCYP2C9
Perfluorooctane sulfonic acidCYP2C18NVS_ADME_hCYP2C18
Perfluorooctane sulfonic acidCYP19A1NVS_ADME_hCYP19A1
Perfluorooctane sulfonic acidDRD4NVS_GPCR_hDRD4.4
Perfluorooctane sulfonic acidDUSP3NVS_ENZ_hDUSP3
Perfluorooctane sulfonic acidDYRK1ANVS_ENZ_hDYRK1a
Perfluorooctane sulfonic acidEGFRNVS_ENZ_hEGFR
Perfluorooctane sulfonic acidEPHA2NVS_ENZ_hEphA2
Perfluorooctane sulfonic acidAKT1NVS_ENZ_hAKT1
Perfluorooctane sulfonic acidAKT2NVS_ENZ_hAKT2
Perfluorooctane sulfonic acidESR1ATG_ERa_TRANS_up
Perfluorooctane sulfonic acidESR1OT_ER_ERaERb_0480
Perfluorooctane sulfonic acidESR1ATG_ERE_CIS_up
Perfluorooctane sulfonic acidESR1TOX21_ERa_BLA_Antagonist_ratio
Perfluorooctane sulfonic acidESR1NVS_NR_hER
Perfluorooctane sulfonic acidESR2TOX21_ERb_BLA_Antagonist_ratio
Perfluorooctane sulfonic acidESR2OT_ER_ERaERb_0480
Perfluorooctane sulfonic acidFGFR1NVS_ENZ_hFGFR1
Perfluorooctane sulfonic acidFGFR3NVS_ENZ_hFGFR3
Perfluorooctane sulfonic acidSIRT2NVS_ENZ_hSIRT2
Perfluorooctane sulfonic acidFLT1NVS_ENZ_hVEGFR1
Perfluorooctane sulfonic acidFLT4NVS_ENZ_hVEGFR3
Perfluorooctane sulfonic acidSIRT3NVS_ENZ_hSIRT3_Activator
Perfluorooctane sulfonic acidFOSATG_AP_1_CIS_up
Perfluorooctane sulfonic acidBACE1NVS_ENZ_hBACE
Perfluorooctane sulfonic acidFYNNVS_ENZ_hFyn
Perfluorooctane sulfonic acidNR3C1NVS_NR_hGR
Perfluorooctane sulfonic acidGSK3BNVS_ENZ_hGSK3b
Perfluorooctane sulfonic acidHLA-DRABSK_BE3C_HLADR_down
Perfluorooctane sulfonic acidHTR5ANVS_GPCR_h5HT5A
Perfluorooctane sulfonic acidHTR6NVS_GPCR_h5HT6
Perfluorooctane sulfonic acidHTR7NVS_GPCR_h5HT7
Perfluorooctane sulfonic acidIL1ABSK_BE3C_IL1a_down
Perfluorooctane sulfonic acidCXCL8BSK_LPS_IL8_up
Perfluorooctane sulfonic acidCXCL10BSK_hDFCGF_IP10_down
Perfluorooctane sulfonic acidCXCL10BSK_KF3CT_IP10_down
Perfluorooctane sulfonic acidCXCL10BSK_BE3C_IP10_down
Perfluorooctane sulfonic acidINSRNVS_ENZ_hInsR
Perfluorooctane sulfonic acidINSRNVS_ENZ_hInsR_Activator
Perfluorooctane sulfonic acidARACEA_AR_antagonist_80hr
Perfluorooctane sulfonic acidARNVS_NR_hAR
Perfluorooctane sulfonic acidJUNATG_AP_1_CIS_up
Perfluorooctane sulfonic acidKDRNVS_ENZ_hVEGFR2
Perfluorooctane sulfonic acidLCKNVS_ENZ_hLck
Perfluorooctane sulfonic acidLYNNVS_ENZ_hLynA_Activator
Perfluorooctane sulfonic acidMARK1NVS_ENZ_hMARK1
Perfluorooctane sulfonic acidMETNVS_ENZ_hMet
Perfluorooctane sulfonic acidMMP3NVS_ENZ_hMMP3
Perfluorooctane sulfonic acidMMP7NVS_ENZ_hMMP7
Perfluorooctane sulfonic acidMMP9NVS_ENZ_hMMP9
Perfluorooctane sulfonic acidMMP9BSK_KF3CT_MMP9_down
Perfluorooctane sulfonic acidMMP13NVS_ENZ_hMMP13
Perfluorooctane sulfonic acidMTF1ATG_MRE_CIS_up
Perfluorooctane sulfonic acidNFE2L2TOX21_ARE_BLA_agonist_ratio
Perfluorooctane sulfonic acidNFE2L2ATG_NRF2_ARE_CIS_up
Perfluorooctane sulfonic acidNPY2RNVS_GPCR_hNPY2
Perfluorooctane sulfonic acidNTRK1NVS_ENZ_hTrkA
Perfluorooctane sulfonic acidOPRD1NVS_GPCR_hOpiate_D1
Perfluorooctane sulfonic acidP2RY1NVS_GPCR_hPY2
Perfluorooctane sulfonic acidSERPINE1BSK_BE3C_PAI1_down
Perfluorooctane sulfonic acidPAX6ATG_Pax6_CIS_up
Perfluorooctane sulfonic acidPDE4ANVS_ENZ_hPDE4A1
Perfluorooctane sulfonic acidACP1NVS_ENZ_hACP1
Perfluorooctane sulfonic acidPGRNVS_NR_hPR
Perfluorooctane sulfonic acidPGRTOX21_PR_BLA_Antagonist_ratio
Perfluorooctane sulfonic acidPIK3CANVS_ENZ_hPI3Ka
Perfluorooctane sulfonic acidPLATBSK_BE3C_tPA_down
Perfluorooctane sulfonic acidPLAUBSK_BE3C_uPA_down
Perfluorooctane sulfonic acidPPARAATG_PPARa_TRANS_up
Perfluorooctane sulfonic acidPPARAATG_PPRE_CIS_up
Perfluorooctane sulfonic acidPPARDATG_PPRE_CIS_up
Perfluorooctane sulfonic acidPPARGNVS_NR_hPPARg
Perfluorooctane sulfonic acidPPARGATG_PPRE_CIS_up
Perfluorooctane sulfonic acidPPARGATG_PPARg_TRANS_up
Perfluorooctane sulfonic acidPPP1CANVS_ENZ_hPPP1CA
Perfluorooctane sulfonic acidPPP2CANVS_ENZ_hPPP2CA
Perfluorooctane sulfonic acidPRKAA1NVS_ENZ_hAMPKa1
Perfluorooctane sulfonic acidPRKACANVS_ENZ_hPKA
Perfluorooctane sulfonic acidMAPK1NVS_ENZ_hMAPK1
Perfluorooctane sulfonic acidMAPK3NVS_ENZ_hMAPK3
Perfluorooctane sulfonic acidPTENNVS_ENZ_hPTEN
Perfluorooctane sulfonic acidPTPN1NVS_ENZ_hPTPN1
Perfluorooctane sulfonic acidPTPN2NVS_ENZ_hPTPN2
Perfluorooctane sulfonic acidPTPN6NVS_ENZ_hPTPN6
Perfluorooctane sulfonic acidPTPN11NVS_ENZ_hPTPN11
Perfluorooctane sulfonic acidPTPN12NVS_ENZ_hPTPN12
Perfluorooctane sulfonic acidPTPN13NVS_ENZ_hPTPN13
Perfluorooctane sulfonic acidPTPRBNVS_ENZ_hPTPRB
Perfluorooctane sulfonic acidPTPRCNVS_ENZ_hPTPRC
Perfluorooctane sulfonic acidPTPRFNVS_ENZ_hPTPRF
Perfluorooctane sulfonic acidPTPRMNVS_ENZ_hPTPRM
Perfluorooctane sulfonic acidRAF1NVS_ENZ_hRAF1
Perfluorooctane sulfonic acidRARANVS_NR_hRAR_Antagonist
Perfluorooctane sulfonic acidROCK1NVS_ENZ_hROCK1
Perfluorooctane sulfonic acidSGK1NVS_ENZ_hSGK1
Perfluorooctane sulfonic acidSLC5A5NIS_RAIU_inhibition
Perfluorooctane sulfonic acidCYP4F12NVS_ADME_hCYP4F12
Perfluorooctane sulfonic acidSP1ATG_Sp1_CIS_up
Perfluorooctane sulfonic acidAURKANVS_ENZ_hAurA
Perfluorooctane sulfonic acidTBXA2RNVS_GPCR_hTXA2
Perfluorooctane sulfonic acidBTKNVS_ENZ_hBTK
Perfluorooctane sulfonic acidTEKNVS_ENZ_hTie2
Perfluorooctane sulfonic acidTGFB1BSK_KF3CT_TGFb1_down
Perfluorooctane sulfonic acidTGFB1ATG_TGFb_CIS_up
Perfluorooctane sulfonic acidTGFB1BSK_BE3C_TGFb1_down
Perfluorooctane sulfonic acidTHRANVS_NR_hTRa_Antagonist
Perfluorooctane sulfonic acidTP53APR_HepG2_p53Act_72h_up
Perfluorooctane sulfonic acidTP53TOX21_p53_BLA_p4_ratio
Perfluorooctane sulfonic acidTP53ATG_p53_CIS_dn
Perfluorooctane sulfonic acidTP53APR_HepG2_p53Act_24h_up
Perfluorooctane sulfonic acidNR1H2ATG_DR4_LXR_CIS_dn
Perfluorooctane sulfonic acidVCAM1BSK_hDFCGF_VCAM1_down
Perfluorooctane sulfonic acidZAP70NVS_ENZ_hZAP70
Perfluorooctane sulfonic acidCASP5NVS_ENZ_hCASP5
Perfluorooctane sulfonic acidMAPKAPK5NVS_ENZ_hMAPKAPK5
Perfluorooctane sulfonic acidPDE5ANVS_ENZ_hPDE5
Perfluorooctane sulfonic acidHDAC3NVS_ENZ_hHDAC3
Perfluorooctane sulfonic acidNR1I2ATG_PXRE_CIS_up
Perfluorooctane sulfonic acidNR1I2NVS_NR_hPXR
Perfluorooctane sulfonic acidNR1I2ATG_PXR_TRANS_up
Perfluorooctane sulfonic acidRPS6KA5NVS_ENZ_hMsk1
Perfluorooctane sulfonic acidCD40BSK_SAg_CD40_down
Perfluorooctane sulfonic acidNR1I3NVS_NR_hCAR_Antagonist

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