Triclocarban

Target genes for Triclocarban is obtained based on ToxCast assay component endpoints.
Chemical nameGene identifierToxCast assay component endpoint name
TriclocarbanNR1H3ATG_DR4_LXR_CIS_dn
TriclocarbanNACEETOX_H295R_PROG_dn
TriclocarbanCCL26BSK_4H_Eotaxin3_down
TriclocarbanCREB3ATG_CRE_CIS_up
TriclocarbanCOL3A1BSK_hDFCGF_CollagenIII_down
TriclocarbanCSF1BSK_CASM3C_MCSF_down
TriclocarbanCSF1BSK_hDFCGF_MCSF_down
TriclocarbanCSF1BSK_LPS_MCSF_down
TriclocarbanCYP2C19NVS_ADME_hCYP2C19
TriclocarbanCYP19A1TOX21_Aromatase_Inhibition
TriclocarbanEGFRBSK_hDFCGF_EGFR_down
TriclocarbanAHRTOX21_AhR_LUC_Agonist
TriclocarbanESR1TOX21_ERa_LUC_VM7_Antagonist_0.5nM_E2
TriclocarbanESR1TOX21_ERa_LUC_VM7_Antagonist_0.1nM_E2
TriclocarbanESR1TOX21_ERa_BLA_Antagonist_ratio
TriclocarbanESR2TOX21_ERb_BLA_Antagonist_ratio
TriclocarbanESRRATOX21_ERR_Antagonist
TriclocarbanESRRATOX21_PGC_ERR_Antagonist
TriclocarbanF3BSK_LPS_TissueFactor_down
TriclocarbanF3BSK_CASM3C_TissueFactor_down
TriclocarbanFOSATG_AP_1_CIS_up
TriclocarbanBACE1NVS_ENZ_hBACE
TriclocarbanNR3C1CEETOX_H295R_DOC_dn
TriclocarbanNR3C1CEETOX_H295R_11DCORT_dn
TriclocarbanHIF1AATG_HIF1a_CIS_up
TriclocarbanHLA-DRABSK_BE3C_HLADR_down
TriclocarbanHLA-DRABSK_CASM3C_HLADR_down
TriclocarbanHLA-DRABSK_3C_HLADR_down
TriclocarbanIL1ABSK_LPS_IL1a_down
TriclocarbanIL6BSK_CASM3C_IL6_up
TriclocarbanCXCL8BSK_SAg_IL8_down
TriclocarbanCXCL8BSK_3C_IL8_down
TriclocarbanCXCL8BSK_LPS_IL8_down
TriclocarbanCXCL10BSK_hDFCGF_IP10_down
TriclocarbanCXCL10BSK_BE3C_IP10_down
TriclocarbanIRF1ATG_ISRE_CIS_dn
TriclocarbanARTOX21_AR_LUC_MDAKB2_Antagonist_0.5nM_R1881
TriclocarbanARTOX21_AR_BLA_Antagonist_ratio
TriclocarbanARACEA_AR_antagonist_80hr
TriclocarbanARTOX21_AR_LUC_MDAKB2_Antagonist_10nM_R1881
TriclocarbanAROT_AR_ARSRC1_0960
TriclocarbanJUNTOX21_AP1_BLA_Agonist_ratio
TriclocarbanJUNATG_AP_1_CIS_up
TriclocarbanKDRBSK_4H_VEGFRII_down
TriclocarbanLDLRBSK_CASM3C_LDLR_down
TriclocarbanFOSTOX21_AP1_BLA_Agonist_ratio
TriclocarbanSMAD1ATG_BRE_CIS_up
TriclocarbanCXCL9BSK_hDFCGF_MIG_down
TriclocarbanCXCL9BSK_SAg_MIG_down
TriclocarbanNR3C2CEETOX_H295R_DOC_dn
TriclocarbanNR3C2CEETOX_H295R_11DCORT_dn
TriclocarbanMMP1BSK_hDFCGF_MMP1_up
TriclocarbanMMP9BSK_KF3CT_MMP9_down
TriclocarbanNFE2L2ATG_NRF2_ARE_CIS_up
TriclocarbanSERPINE1BSK_hDFCGF_PAI1_down
TriclocarbanSERPINE1BSK_BE3C_PAI1_down
TriclocarbanPGRTOX21_PR_BLA_Antagonist_ratio
TriclocarbanPGRCEETOX_H295R_OHPREG_dn
TriclocarbanPGRCEETOX_H295R_OHPROG_dn
TriclocarbanPGRCEETOX_H295R_PROG_dn
TriclocarbanPLATBSK_BE3C_tPA_down
TriclocarbanPLAURBSK_BE3C_uPAR_down
TriclocarbanPLAURBSK_3C_uPAR_down
TriclocarbanPLAURBSK_CASM3C_uPAR_down
TriclocarbanPLAURBSK_4H_uPAR_down
TriclocarbanPOU2F1ATG_Oct_MLP_CIS_up
TriclocarbanPPARDTOX21_PPARd_BLA_antagonist_ratio
TriclocarbanPTGER2BSK_LPS_PGE2_down
TriclocarbanRORAATG_RORE_CIS_up
TriclocarbanRORBATG_RORE_CIS_up
TriclocarbanRORCATG_RORE_CIS_up
TriclocarbanRXRAOT_NURR1_NURR1RXRa_0480
TriclocarbanSAA1BSK_CASM3C_SAA_down
TriclocarbanCCL2BSK_LPS_MCP1_down
TriclocarbanCCL2BSK_4H_MCP1_down
TriclocarbanCCL2BSK_SAg_MCP1_down
TriclocarbanCCL2BSK_3C_MCP1_down
TriclocarbanSELEBSK_3C_Eselectin_down
TriclocarbanSELEBSK_LPS_Eselectin_down
TriclocarbanSELEBSK_SAg_Eselectin_down
TriclocarbanSELPBSK_4H_Pselectin_down
TriclocarbanSLC5A5NIS_RAIU_inhibition
TriclocarbanSLC6A4NVS_TR_hSERT
TriclocarbanTNFBSK_LPS_TNFa_down
TriclocarbanTP53TOX21_p53_BLA_p4_ratio
TriclocarbanTP53TOX21_p53_BLA_p1_ratio
TriclocarbanTP53APR_HepG2_p53Act_72h_up
TriclocarbanTP53APR_HepG2_p53Act_24h_up
TriclocarbanTP53TOX21_p53_BLA_p5_ratio
TriclocarbanTP53TOX21_p53_BLA_p2_ratio
TriclocarbanTP53TOX21_p53_BLA_p3_ratio
TriclocarbanTSHRTOX21_TSHR_Antagonist_ratio
TriclocarbanNR1H2ATG_DR4_LXR_CIS_dn
TriclocarbanVCAM1BSK_3C_VCAM1_down
TriclocarbanVCAM1BSK_4H_VCAM1_down
TriclocarbanVCAM1BSK_hDFCGF_VCAM1_down
TriclocarbanVCAM1BSK_LPS_VCAM1_down
TriclocarbanVDRATG_VDRE_CIS_up
TriclocarbanXBP1ATG_Xbp1_CIS_up
TriclocarbanNR1I2ATG_PXRE_CIS_dn
TriclocarbanCD38BSK_SAg_CD38_down
TriclocarbanCD40BSK_LPS_CD40_down
TriclocarbanCD40BSK_SAg_CD40_down
TriclocarbanCD69BSK_SAg_CD69_down
TriclocarbanNR1I3TOX21_CAR_Antagonist
TriclocarbanNR1I3TOX21_CAR_Agonist
TriclocarbanNR1H4TOX21_FXR_BLA_antagonist_ratio

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