Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-

Target genes for Phenol, 4,4'-(9H-fluoren-9-ylidene)bis- is obtained based on ToxCast assay component endpoints.
Chemical nameGene identifierToxCast assay component endpoint name
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-NR1H3ATG_DR4_LXR_CIS_dn
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-ESR1ATG_ERE_CIS_dn
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-CREB3ATG_CRE_CIS_up
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-CEBPBATG_C_EBP_CIS_dn
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-CYP19A1TOX21_Aromatase_Inhibition
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-CYP24A1TOX21_VDR_BLA_agonist_ratio
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-CYP24A1TOX21_VDR_BLA_antagonist_ratio
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-E2F1ATG_E2F_CIS_dn
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-EGR1ATG_EGR_CIS_up
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-AHRATG_Ahr_CIS_up
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-ESR1TOX21_ERa_LUC_VM7_Antagonist_0.1nM_E2
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-ESR1TOX21_ERa_BLA_Agonist_ratio
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-ESR1NVS_NR_hER
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-ESR1ATG_ERE_CIS_dn
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-ESR1TOX21_ERa_BLA_Antagonist_ratio
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-ESR1TOX21_ERa_LUC_VM7_Antagonist_0.5nM_E2
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-ESR2TOX21_ERb_BLA_Antagonist_ratio
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-ESRRATOX21_PGC_ERR_Antagonist
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-ESRRATOX21_ERR_Antagonist
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-ETS1ATG_Ets_CIS_up
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-ATF6TOX21_ESRE_BLA_ratio
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-FOXO1ATG_FoxO_CIS_dn
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-FOXO3ATG_FoxO_CIS_dn
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-GATA1ATG_GATA_CIS_dn
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-GLI1ATG_GLI_CIS_up
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-NR3C1TOX21_GR_BLA_Antagonist_ratio
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-NR3C1TOX21_GR_BLA_Agonist_ratio
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-HIF1AATG_HIF1a_CIS_up
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-HIF1ATOX21_HRE_BLA_Agonist_ratio
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-ONECUT1ATG_HNF6_CIS_dn
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-HSF1TOX21_HSE_BLA_agonist_ratio
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-HSF1ATG_HSE_CIS_up
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-IRF1ATG_ISRE_CIS_dn
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-ARTOX21_AR_BLA_Antagonist_ratio
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-ARTOX21_AR_LUC_MDAKB2_Antagonist_0.5nM_R1881
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-ARTOX21_AR_LUC_MDAKB2_Antagonist_10nM_R1881
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-JUNTOX21_AP1_BLA_Agonist_ratio
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-ESR1ATG_ERE_CIS_dn
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-FOSTOX21_AP1_BLA_Agonist_ratio
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-NAATG_ERE_CIS_dn
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-MTF1ATG_MRE_CIS_up
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-MYBATG_Myb_CIS_dn
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-NFIAATG_NFI_CIS_up
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-NFE2L2TOX21_ARE_BLA_agonist_ratio
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-NFKB1TOX21_NFkB_BLA_agonist_ratio
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-NFKB1ATG_NF_kB_CIS_dn
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-NRF1ATG_NRF1_CIS_dn
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-PAX6ATG_Pax6_CIS_up
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-PGRTOX21_PR_BLA_Antagonist_ratio
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-POU2F1ATG_Oct_MLP_CIS_up
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-PPARAATG_PPRE_CIS_dn
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-PPARDTOX21_PPARd_BLA_agonist_ratio
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-PPARDATG_PPRE_CIS_dn
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-PPARDTOX21_PPARd_BLA_antagonist_ratio
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-PPARGATG_PPRE_CIS_dn
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-PPARGTOX21_PPARg_BLA_antagonist_ratio
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-PPARGTOX21_PPARg_BLA_Agonist_ratio
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-RARAATG_RARa_TRANS_dn
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-RORAATG_RORE_CIS_up
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-RORBATG_RORE_CIS_up
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-RORBATG_RORb_TRANS_dn
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-RORCATG_RORE_CIS_up
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-RXRAATG_RXRa_TRANS_up
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-RXRATOX21_RXR_BLA_Agonist_ratio
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-RXRBATG_RXRb_TRANS_dn
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-SREBF1ATG_SREBP_CIS_up
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-STAT3ATG_STAT3_CIS_dn
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-TP53ATG_p53_CIS_dn
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-TP53TOX21_p53_BLA_p3_ratio
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-TP53TOX21_p53_BLA_p4_ratio
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-TP53TOX21_p53_BLA_p2_ratio
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-TP53TOX21_p53_BLA_p5_ratio
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-TP53TOX21_p53_BLA_p1_ratio
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-TSHRTOX21_TSHR_Agonist_ratio
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-NR1H2ATG_DR4_LXR_CIS_dn
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-USF1ATG_E_Box_CIS_dn
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-VDRTOX21_VDR_BLA_agonist_ratio
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-VDRTOX21_VDR_BLA_antagonist_ratio
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-VDRATG_VDRE_CIS_up
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-XBP1ATG_Xbp1_CIS_up
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-NR1I2ATG_PXRE_CIS_up
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-NR1I2ATG_PXR_TRANS_up
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-NR1I3TOX21_CAR_Antagonist
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-NR1H4ATG_FXR_TRANS_up
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-NR1H4TOX21_FXR_BLA_agonist_ratio
Phenol, 4,4'-(9H-fluoren-9-ylidene)bis-NR1H4TOX21_FXR_BLA_antagonist_ratio

DISCLAIMER

We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.