Tetradifon

Target genes for Tetradifon is obtained based on ToxCast assay component endpoints.
Chemical nameGene identifierToxCast assay component endpoint name
TetradifonNR1H3ATG_LXRa_TRANS_dn
TetradifonNR1H3ATG_DR4_LXR_CIS_dn
TetradifonCREB3ATG_CRE_CIS_dn
TetradifonCEBPBATG_C_EBP_CIS_dn
TetradifonCOL3A1BSK_hDFCGF_CollagenIII_down
TetradifonCYP19A1TOX21_Aromatase_Inhibition
TetradifonESR1TOX21_ERa_BLA_Antagonist_ratio
TetradifonESR1TOX21_ERa_LUC_VM7_Antagonist_0.1nM_E2
TetradifonESR1TOX21_ERa_LUC_VM7_Antagonist_0.5nM_E2
TetradifonESR2TOX21_ERb_BLA_Antagonist_ratio
TetradifonESRRATOX21_PGC_ERR_Antagonist
TetradifonESRRATOX21_ERR_Antagonist
TetradifonF3BSK_CASM3C_TissueFactor_down
TetradifonFLT1NVS_ENZ_hVEGFR1_Activator
TetradifonFOSATG_AP_1_CIS_up
TetradifonHIF1AATG_HIF1a_CIS_dn
TetradifonHLA-DRABSK_3C_HLADR_down
TetradifonHLA-DRABSK_BE3C_HLADR_down
TetradifonIL6BSK_CASM3C_IL6_down
TetradifonCXCL8BSK_3C_IL8_down
TetradifonARTOX21_AR_LUC_MDAKB2_Antagonist_10nM_R1881
TetradifonARTOX21_AR_BLA_Antagonist_ratio
TetradifonARTOX21_AR_LUC_MDAKB2_Antagonist_0.5nM_R1881
TetradifonJUNATG_AP_1_CIS_up
TetradifonJUNTOX21_AP1_BLA_Agonist_ratio
TetradifonFOSTOX21_AP1_BLA_Agonist_ratio
TetradifonMMP9BSK_KF3CT_MMP9_down
TetradifonNFE2L2ATG_NRF2_ARE_CIS_up
TetradifonNFE2L2TOX21_ARE_BLA_agonist_ratio
TetradifonSERPINE1BSK_hDFCGF_PAI1_down
TetradifonPGRTOX21_PR_BLA_Antagonist_ratio
TetradifonPLAURBSK_3C_uPAR_down
TetradifonPLAURBSK_CASM3C_uPAR_up
TetradifonPPARAATG_PPARa_TRANS_dn
TetradifonPPARGATG_PPARg_TRANS_up
TetradifonPPARGTOX21_PPARg_BLA_antagonist_ratio
TetradifonRARAATG_DR5_CIS_dn
TetradifonRARBATG_DR5_CIS_dn
TetradifonRARGATG_DR5_CIS_dn
TetradifonCCL2BSK_KF3CT_MCP1_up
TetradifonSELEBSK_3C_Eselectin_down
TetradifonSREBF1ATG_SREBP_CIS_up
TetradifonTGFB1BSK_KF3CT_TGFb1_down
TetradifonTHBDBSK_CASM3C_Thrombomodulin_up
TetradifonTIMP2BSK_KF3CT_TIMP2_down
TetradifonTP53TOX21_p53_BLA_p1_ratio
TetradifonTSHRTOX21_TSHR_Antagonist_ratio
TetradifonNR1H2ATG_DR4_LXR_CIS_dn
TetradifonUSF1ATG_E_Box_CIS_up
TetradifonVCAM1BSK_CASM3C_VCAM1_down
TetradifonVDRATG_VDRE_CIS_up
TetradifonNR1I2ATG_PXR_TRANS_up
TetradifonNR1I2ATG_PXRE_CIS_up
TetradifonCD38BSK_SAg_CD38_down
TetradifonNR1I3TOX21_CAR_Agonist
TetradifonNR1H4TOX21_FXR_BLA_antagonist_ratio
TetradifonNR1H4ATG_IR1_CIS_dn

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