Benzyl salicylate

Target genes for Benzyl salicylate is obtained based on ToxCast assay component endpoints.
Chemical nameGene identifierToxCast assay component endpoint name
Benzyl salicylateNR1H3ATG_DR4_LXR_CIS_dn
Benzyl salicylateNACEETOX_H295R_PROG_dn
Benzyl salicylateAHRATG_Ahr_CIS_up
Benzyl salicylateESR1OT_ER_ERaERb_0480
Benzyl salicylateESR1ATG_ERE_CIS_up
Benzyl salicylateESR1ATG_ERa_TRANS_up
Benzyl salicylateESR1OT_ER_ERaERb_1440
Benzyl salicylateESR1OT_ER_ERaERa_0480
Benzyl salicylateESR1TOX21_ERa_LUC_VM7_Agonist
Benzyl salicylateESR2OT_ER_ERbERb_0480
Benzyl salicylateESR2OT_ER_ERbERb_1440
Benzyl salicylateESR2OT_ER_ERaERb_1440
Benzyl salicylateESR2OT_ER_ERaERb_0480
Benzyl salicylateESRRATOX21_ERR_Agonist
Benzyl salicylateFOSATG_AP_1_CIS_up
Benzyl salicylateNR3C1CEETOX_H295R_CORTIC_up
Benzyl salicylateHDAC1TOX21_HDAC_Inhibition
Benzyl salicylateJUNATG_AP_1_CIS_up
Benzyl salicylateJUNTOX21_AP1_BLA_Agonist_ratio
Benzyl salicylateFOSTOX21_AP1_BLA_Agonist_ratio
Benzyl salicylateSMAD1ATG_BRE_CIS_up
Benzyl salicylateNR3C2CEETOX_H295R_CORTIC_up
Benzyl salicylateMTF1ATG_MRE_CIS_up
Benzyl salicylateNFIAATG_NFI_CIS_up
Benzyl salicylateNFE2L2ATG_NRF2_ARE_CIS_up
Benzyl salicylatePGRCEETOX_H295R_PROG_dn
Benzyl salicylatePGRCEETOX_H295R_OHPROG_dn
Benzyl salicylatePGRTOX21_PR_BLA_Antagonist_ratio
Benzyl salicylatePOU2F1ATG_Oct_MLP_CIS_up
Benzyl salicylatePPARGATG_PPARg_TRANS_up
Benzyl salicylateRARAATG_RARa_TRANS_dn
Benzyl salicylateRARBATG_RARb_TRANS_dn
Benzyl salicylateRXRBATG_RXRb_TRANS_up
Benzyl salicylateSP1ATG_Sp1_CIS_up
Benzyl salicylateSREBF1ATG_SREBP_CIS_up
Benzyl salicylateTGFB1ATG_TGFb_CIS_up
Benzyl salicylateTP53ATG_p53_CIS_up
Benzyl salicylateNR1H2ATG_DR4_LXR_CIS_dn
Benzyl salicylateXBP1ATG_Xbp1_CIS_up
Benzyl salicylateNR1I2ATG_PXRE_CIS_up
Benzyl salicylateNR1I2ATG_PXR_TRANS_up

DISCLAIMER

We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.