Folpet

Target genes for Folpet is obtained based on ToxCast assay component endpoints.
Chemical nameGene identifierToxCast assay component endpoint name
FolpetCOL3A1BSK_hDFCGF_CollagenIII_down
FolpetCSF1BSK_hDFCGF_MCSF_down
FolpetCSF1BSK_CASM3C_MCSF_down
FolpetCYP2C19NVS_ADME_hCYP2C19
FolpetCYP2C8NVS_ADME_hCYP2C8
FolpetCYP19A1TOX21_Aromatase_Inhibition
FolpetCYP19A1NVS_ADME_hCYP19A1
FolpetCYP24A1TOX21_VDR_BLA_antagonist_ratio
FolpetDRD1NVS_GPCR_hDRD1
FolpetESR1TOX21_ERa_BLA_Antagonist_ratio
FolpetESR1TOX21_ERa_LUC_VM7_Antagonist_0.1nM_E2
FolpetESR1TOX21_ERa_LUC_VM7_Antagonist_0.5nM_E2
FolpetESR1ATG_ERa_TRANS_up
FolpetESR2TOX21_ERb_BLA_Antagonist_ratio
FolpetESRRATOX21_ERR_Antagonist
FolpetESRRATOX21_PGC_ERR_Antagonist
FolpetNR3C1TOX21_GR_BLA_Antagonist_ratio
FolpetHIF1ATOX21_HRE_BLA_Agonist_ratio
FolpetHLA-DRABSK_CASM3C_HLADR_down
FolpetHLA-DRABSK_BE3C_HLADR_down
FolpetHSF1TOX21_HSE_BLA_agonist_ratio
FolpetHTR6NVS_GPCR_h5HT6
FolpetICAM1BSK_KF3CT_ICAM1_down
FolpetIL1ABSK_BE3C_IL1a_down
FolpetIL6BSK_CASM3C_IL6_down
FolpetCXCL8BSK_CASM3C_IL8_down
FolpetCXCL10BSK_hDFCGF_IP10_down
FolpetCXCL10BSK_KF3CT_IP10_down
FolpetCXCL10BSK_BE3C_IP10_down
FolpetARTOX21_AR_BLA_Antagonist_ratio
FolpetARTOX21_AR_LUC_MDAKB2_Antagonist_10nM_R1881
FolpetAROT_AR_ARSRC1_0960
FolpetAROT_AR_ARSRC1_0480
FolpetARACEA_AR_antagonist_80hr
FolpetARTOX21_AR_LUC_MDAKB2_Antagonist_0.5nM_R1881
FolpetJUNTOX21_AP1_BLA_Agonist_ratio
FolpetLDLRBSK_CASM3C_LDLR_down
FolpetFOSTOX21_AP1_BLA_Agonist_ratio
FolpetCXCL9BSK_CASM3C_MIG_down
FolpetCXCL9BSK_BE3C_MIG_down
FolpetCXCL9BSK_hDFCGF_MIG_down
FolpetMMP1BSK_BE3C_MMP1_down
FolpetNFE2L2ATG_NRF2_ARE_CIS_up
FolpetNFE2L2TOX21_ARE_BLA_agonist_ratio
FolpetOPRM1NVS_GPCR_hOpiate_mu
FolpetSERPINE1BSK_BE3C_PAI1_down
FolpetPGRTOX21_PR_BLA_Antagonist_ratio
FolpetPLAUBSK_BE3C_uPA_down
FolpetPLAURBSK_CASM3C_uPAR_down
FolpetPLAURBSK_BE3C_uPAR_down
FolpetPPARDTOX21_PPARd_BLA_antagonist_ratio
FolpetPPARGTOX21_PPARg_BLA_antagonist_ratio
FolpetCCL2BSK_CASM3C_MCP1_down
FolpetSLC5A5NIS_RAIU_inhibition
FolpetSREBF1ATG_SREBP_CIS_up
FolpetTGFB1BSK_BE3C_TGFb1_down
FolpetTHBDBSK_CASM3C_Thrombomodulin_up
FolpetTNFBSK_LPS_TNFa_down
FolpetTP53TOX21_p53_BLA_p1_ratio
FolpetTP53TOX21_p53_BLA_p4_ratio
FolpetTP53TOX21_p53_BLA_p5_ratio
FolpetTP53TOX21_p53_BLA_p2_ratio
FolpetTP53TOX21_p53_BLA_p3_ratio
FolpetTSHRTOX21_TSHR_Agonist_ratio
FolpetVCAM1BSK_CASM3C_VCAM1_down
FolpetVCAM1BSK_hDFCGF_VCAM1_down
FolpetVDRTOX21_VDR_BLA_antagonist_ratio
FolpetNR1I2ATG_PXRE_CIS_up
FolpetNR1I3TOX21_CAR_Antagonist
FolpetNR1H4TOX21_FXR_BLA_antagonist_ratio

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