Perfluorooctanoic acid

Target genes for Perfluorooctanoic acid is obtained based on ToxCast assay component endpoints.
Chemical nameGene identifierToxCast assay component endpoint name
Perfluorooctanoic acidNR1H3ATG_DR4_LXR_CIS_dn
Perfluorooctanoic acidNAATG_THRa1_TRANS_dn
Perfluorooctanoic acidLTB4RNVS_GPCR_hLTB4_BLT1
Perfluorooctanoic acidADORA2ANVS_GPCR_hAdoRA2a
Perfluorooctanoic acidCYP2B6CLD_CYP2B6_24hr
Perfluorooctanoic acidESR1TOX21_ERa_BLA_Antagonist_ratio
Perfluorooctanoic acidESR1ATG_ERa_TRANS_up
Perfluorooctanoic acidESR1ATG_ERE_CIS_up
Perfluorooctanoic acidESR2TOX21_ERb_BLA_Antagonist_ratio
Perfluorooctanoic acidESRRATOX21_ERR_Antagonist
Perfluorooctanoic acidFOSATG_AP_1_CIS_up
Perfluorooctanoic acidBACE1NVS_ENZ_hBACE
Perfluorooctanoic acidGSTA2CLD_GSTA2_48hr
Perfluorooctanoic acidHMGCS2CLD_HMGCS2_48hr
Perfluorooctanoic acidICAM1BSK_KF3CT_ICAM1_down
Perfluorooctanoic acidJUNATG_AP_1_CIS_up
Perfluorooctanoic acidMMP1BSK_BE3C_MMP1_up
Perfluorooctanoic acidNFE2L2ATG_NRF2_ARE_CIS_up
Perfluorooctanoic acidNFE2L2TOX21_ARE_BLA_agonist_ratio
Perfluorooctanoic acidACP1NVS_ENZ_hACP1
Perfluorooctanoic acidPIK3CANVS_ENZ_hPI3Ka
Perfluorooctanoic acidPLAURBSK_3C_uPAR_down
Perfluorooctanoic acidPPARAATG_PPRE_CIS_up
Perfluorooctanoic acidPPARAATG_PPARa_TRANS_up
Perfluorooctanoic acidPPARDATG_PPRE_CIS_up
Perfluorooctanoic acidPPARDTOX21_PPARd_BLA_antagonist_ratio
Perfluorooctanoic acidPPARDTOX21_PPARd_BLA_agonist_ratio
Perfluorooctanoic acidPPARGATG_PPARg_TRANS_up
Perfluorooctanoic acidPPARGATG_PPRE_CIS_up
Perfluorooctanoic acidPPARGNVS_NR_hPPARg
Perfluorooctanoic acidPPARGTOX21_PPARg_BLA_antagonist_ratio
Perfluorooctanoic acidPPP1CANVS_ENZ_hPPP1CA
Perfluorooctanoic acidPPP2CANVS_ENZ_hPPP2CA
Perfluorooctanoic acidRORAATG_RORE_CIS_dn
Perfluorooctanoic acidRORBATG_RORE_CIS_dn
Perfluorooctanoic acidRORCATG_RORE_CIS_dn
Perfluorooctanoic acidRXRATOX21_RXR_BLA_Agonist_ratio
Perfluorooctanoic acidSELEBSK_LPS_Eselectin_up
Perfluorooctanoic acidSP1ATG_Sp1_CIS_up
Perfluorooctanoic acidTEKNVS_ENZ_hTie2
Perfluorooctanoic acidTHRAATG_THRa1_TRANS_dn
Perfluorooctanoic acidTNFBSK_LPS_TNFa_down
Perfluorooctanoic acidNR1H2ATG_DR4_LXR_CIS_dn
Perfluorooctanoic acidNR1I2ATG_PXRE_CIS_up
Perfluorooctanoic acidNR1I3NVS_NR_hCAR_Antagonist

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