Cyproterone acetate

Target genes for Cyproterone acetate is obtained based on ToxCast assay component endpoints.
Chemical nameGene identifierToxCast assay component endpoint name
Cyproterone acetateNR1H3ATG_DR4_LXR_CIS_dn
Cyproterone acetateNACEETOX_H295R_PROG_dn
Cyproterone acetateCOL3A1BSK_hDFCGF_CollagenIII_down
Cyproterone acetateCSF1BSK_LPS_MCSF_down
Cyproterone acetateEGR1ATG_EGR_CIS_up
Cyproterone acetateESR1TOX21_ERa_BLA_Antagonist_ratio
Cyproterone acetateESR1ACEA_ER_80hr
Cyproterone acetateESR2TOX21_ERb_BLA_Antagonist_ratio
Cyproterone acetateESRRATOX21_ERR_Antagonist
Cyproterone acetateESRRATOX21_PGC_ERR_Antagonist
Cyproterone acetateF3BSK_CASM3C_TissueFactor_up
Cyproterone acetateFOSATG_AP_1_CIS_up
Cyproterone acetateNR3C1CEETOX_H295R_CORTISOL_dn
Cyproterone acetateNR3C1CEETOX_H295R_DOC_dn
Cyproterone acetateNR3C1CEETOX_H295R_CORTIC_dn
Cyproterone acetateNR3C1CEETOX_H295R_11DCORT_dn
Cyproterone acetateNR3C1NVS_NR_hGR
Cyproterone acetateNR3C1TOX21_GR_BLA_Antagonist_ratio
Cyproterone acetateHLA-DRABSK_BE3C_HLADR_down
Cyproterone acetateHSF1ATG_HSE_CIS_up
Cyproterone acetateIL1ABSK_BE3C_IL1a_down
Cyproterone acetateCXCL10BSK_BE3C_IP10_down
Cyproterone acetateARTOX21_AR_BLA_Antagonist_ratio
Cyproterone acetateAROT_AR_ARSRC1_0960
Cyproterone acetateARTOX21_AR_LUC_MDAKB2_Antagonist_0.5nM_R1881
Cyproterone acetateAROT_AR_ARSRC1_0480
Cyproterone acetateARTOX21_AR_LUC_MDAKB2_Agonist
Cyproterone acetateARTOX21_AR_LUC_MDAKB2_Agonist_3uM_Nilutamide
Cyproterone acetateARNVS_NR_hAR
Cyproterone acetateARACEA_AR_antagonist_80hr
Cyproterone acetateJUNATG_AP_1_CIS_up
Cyproterone acetateKDRBSK_4H_VEGFRII_down
Cyproterone acetateSMAD1ATG_BRE_CIS_up
Cyproterone acetateCXCL9BSK_BE3C_MIG_down
Cyproterone acetateNR3C2CEETOX_H295R_DOC_dn
Cyproterone acetateNR3C2CEETOX_H295R_CORTISOL_dn
Cyproterone acetateNR3C2CEETOX_H295R_CORTIC_dn
Cyproterone acetateNR3C2CEETOX_H295R_11DCORT_dn
Cyproterone acetateMMP1BSK_BE3C_MMP1_up
Cyproterone acetateMTF1ATG_MRE_CIS_up
Cyproterone acetateMYCATG_Myc_CIS_up
Cyproterone acetateNFE2L2TOX21_ARE_BLA_agonist_ratio
Cyproterone acetateNFE2L2ATG_NRF2_ARE_CIS_up
Cyproterone acetateOPRM1NVS_GPCR_hOpiate_mu
Cyproterone acetateSERPINE1BSK_BE3C_PAI1_down
Cyproterone acetateSERPINE1BSK_hDFCGF_PAI1_down
Cyproterone acetatePAX6ATG_Pax6_CIS_up
Cyproterone acetateLEF1ATG_TCF_b_cat_CIS_dn
Cyproterone acetatePGRTOX21_PR_BLA_Agonist_ratio
Cyproterone acetatePGRCEETOX_H295R_OHPROG_dn
Cyproterone acetatePGRCEETOX_H295R_OHPREG_up
Cyproterone acetatePGRTOX21_PR_BLA_Antagonist_ratio
Cyproterone acetatePGRNVS_NR_hPR
Cyproterone acetatePGRCEETOX_H295R_PROG_dn
Cyproterone acetatePLAURBSK_4H_uPAR_down
Cyproterone acetatePLAURBSK_BE3C_uPAR_down
Cyproterone acetatePOU2F1ATG_Oct_MLP_CIS_up
Cyproterone acetatePPARGTOX21_PPARg_BLA_antagonist_ratio
Cyproterone acetatePTGER2BSK_LPS_PGE2_up
Cyproterone acetateSLC5A5NIS_RAIU_inhibition
Cyproterone acetateSP1ATG_Sp1_CIS_up
Cyproterone acetateSREBF1ATG_SREBP_CIS_up
Cyproterone acetateTCF7ATG_TCF_b_cat_CIS_dn
Cyproterone acetateTCF7L2ATG_TCF_b_cat_CIS_dn
Cyproterone acetateTFAP2AATG_AP_2_CIS_dn
Cyproterone acetateTFAP2BATG_AP_2_CIS_dn
Cyproterone acetateTGFB1BSK_BE3C_TGFb1_down
Cyproterone acetateTP53ATG_p53_CIS_dn
Cyproterone acetateNR1H2ATG_DR4_LXR_CIS_dn
Cyproterone acetateUSF1ATG_E_Box_CIS_dn
Cyproterone acetateVCAM1BSK_4H_VCAM1_down
Cyproterone acetateVCAM1BSK_LPS_VCAM1_down
Cyproterone acetateXBP1ATG_Xbp1_CIS_up
Cyproterone acetateTCF7L1ATG_TCF_b_cat_CIS_dn
Cyproterone acetateTFAP2DATG_AP_2_CIS_dn
Cyproterone acetateNR1I2ATG_PXRE_CIS_up
Cyproterone acetateCD40BSK_SAg_CD40_down
Cyproterone acetateCD40BSK_LPS_CD40_down
Cyproterone acetateCD69BSK_SAg_CD69_down
Cyproterone acetateNR1I3ATG_CAR_TRANS_dn
Cyproterone acetateNR1H4OT_FXR_FXRSRC1_0480
Cyproterone acetateNR1H4TOX21_FXR_BLA_antagonist_ratio
Cyproterone acetateNR1H4OT_FXR_FXRSRC1_1440
Cyproterone acetateNR1H4ATG_IR1_CIS_dn

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We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.