Parathion

Target genes for Parathion is obtained based on ToxCast assay component endpoints.
Chemical nameGene identifierToxCast assay component endpoint name
ParathionNACEETOX_H295R_PROG_up
ParathionESR1CEETOX_H295R_ESTRONE_up
ParathionCREB3ATG_CRE_CIS_up
ParathionCEBPBATG_C_EBP_CIS_up
ParathionCHRM3NVS_GPCR_hM3
ParathionCHRM4NVS_GPCR_hM4
ParathionCSF1BSK_hDFCGF_MCSF_down
ParathionCSF1BSK_LPS_MCSF_down
ParathionCYP1A1CLD_CYP1A1_48hr
ParathionCYP1A1CLD_CYP1A1_24hr
ParathionCYP1A1CLD_CYP1A1_6hr
ParathionCYP1A1NVS_ADME_hCYP1A1
ParathionCYP1A2NVS_ADME_hCYP1A2
ParathionCYP1A2CLD_CYP1A2_6hr
ParathionCYP1A2CLD_CYP1A2_24hr
ParathionCYP1A2CLD_CYP1A2_48hr
ParathionCYP2B6CLD_CYP2B6_48hr
ParathionCYP2B6NVS_ADME_hCYP2B6
ParathionCYP2B6CLD_CYP2B6_6hr
ParathionCYP2B6CLD_CYP2B6_24hr
ParathionCYP2C19NVS_ADME_hCYP2C19
ParathionCYP2C9NVS_ADME_hCYP2C9
ParathionCYP2C18NVS_ADME_hCYP2C18
ParathionCYP2J2NVS_ADME_hCYP2J2
ParathionCYP3A4CLD_CYP3A4_48hr
ParathionCYP3A4CLD_CYP3A4_24hr
ParathionEGR1ATG_EGR_CIS_up
ParathionAHRTOX21_AhR_LUC_Agonist
ParathionAHRATG_Ahr_CIS_up
ParathionESR1ATG_ERE_CIS_up
ParathionESR1CEETOX_H295R_ESTRONE_up
ParathionESR1ATG_ERa_TRANS_up
ParathionESR2CEETOX_H295R_ESTRONE_up
ParathionFOSATG_AP_1_CIS_up
ParathionNR3C1CEETOX_H295R_11DCORT_dn
ParathionNR3C1CEETOX_H295R_DOC_dn
ParathionNR3C1CEETOX_H295R_CORTISOL_dn
ParathionNR3C1NVS_NR_hGR
ParathionICAM1BSK_KF3CT_ICAM1_up
ParathionCXCL10BSK_KF3CT_IP10_down
ParathionCXCL10BSK_hDFCGF_IP10_down
ParathionARNVS_NR_hAR
ParathionARTOX21_AR_LUC_MDAKB2_Antagonist_0.5nM_R1881
ParathionARACEA_AR_antagonist_80hr
ParathionJUNATG_AP_1_CIS_up
ParathionESR1CEETOX_H295R_ESTRONE_up
ParathionNACEETOX_H295R_ESTRONE_up
ParathionSMAD1ATG_BRE_CIS_up
ParathionNR3C2CEETOX_H295R_11DCORT_dn
ParathionNR3C2CEETOX_H295R_CORTISOL_dn
ParathionNR3C2CEETOX_H295R_DOC_dn
ParathionMMP1BSK_hDFCGF_MMP1_up
ParathionMTF1ATG_MRE_CIS_up
ParathionNFE2L2ATG_NRF2_ARE_CIS_up
ParathionSERPINE1BSK_hDFCGF_PAI1_down
ParathionPGRCEETOX_H295R_OHPROG_up
ParathionPGRCEETOX_H295R_PROG_up
ParathionPGRNVS_NR_hPR
ParathionPGRTOX21_PR_BLA_Antagonist_ratio
ParathionPOU2F1ATG_Oct_MLP_CIS_up
ParathionPPARAATG_PPRE_CIS_up
ParathionUGT1A1CLD_UGT1A1_24hr
ParathionUGT1A1CLD_UGT1A1_48hr
ParathionPPARDATG_PPRE_CIS_up
ParathionPPARGATG_PPRE_CIS_up
ParathionPPARGATG_PPARg_TRANS_up
ParathionPTGER2BSK_LPS_PGE2_up
ParathionBCHENVS_ENZ_hES
ParathionRORAATG_RORE_CIS_up
ParathionRORBATG_RORE_CIS_up
ParathionRORCATG_RORE_CIS_up
ParathionCCL2BSK_4H_MCP1_down
ParathionSELEBSK_SAg_Eselectin_down
ParathionSLC5A5NIS_RAIU_inhibition
ParathionSLC6A4NVS_TR_hSERT
ParathionSREBF1ATG_SREBP_CIS_up
ParathionSULT2A1CLD_SULT2A_48hr
ParathionTHBDBSK_CASM3C_Thrombomodulin_up
ParathionTSPONVS_MP_hPBR
ParathionTP53TOX21_p53_BLA_p2_ratio
ParathionVCAM1BSK_LPS_VCAM1_down
ParathionVCAM1BSK_hDFCGF_VCAM1_down
ParathionVDRATG_VDRE_CIS_up
ParathionNR1I2ATG_PXRE_CIS_up
ParathionNR1I2ATG_PXR_TRANS_up
ParathionCD38BSK_SAg_CD38_down
ParathionCD40BSK_LPS_CD40_down
ParathionCD69BSK_SAg_CD69_down
ParathionNR1I3TOX21_CAR_Agonist
ParathionNR1H4OT_FXR_FXRSRC1_1440
ParathionNR1H4OT_FXR_FXRSRC1_0480

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