Anastrozole


Curated chemical-gene interactions from CTD
Entrez gene IDGene symbolInteraction typeReference
1588 CYP19A1 Decreases activity PMID:15837728; PMID:16001952; PMID:16023338; PMID:16023854; PMID:16034487; PMID:16054421; PMID:21341743; PMID:32764486
2488 FSHB Increases expression PMID:10657858
2697 GJA1 Decreases expression PMID:29180066
3972 LHB Increases expression PMID:10657858
4288 MKI67 Decreases expression PMID:15767642; PMID:16002280
5241 PGR Decreases expression PMID:16002280
5447 POR Decreases activity PMID:35206146

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We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.