Aniline


Curated chemical-gene interactions from CTD
Entrez gene IDGene symbolInteraction typeReference
10096 ACTR3 Increases expression PMID:21708182
1017 CDK2 Increases expression PMID:21070798; PMID:28463034
1019 CDK4 Increases expression PMID:21070798; PMID:28463034
1021 CDK6 Increases expression PMID:21070798; PMID:28463034
10294 DNAJA2 Increases expression PMID:22016648
10694 CCT8 Increases expression PMID:21708182
1147 CHUK Increases expression PMID:18420242
114971 PTPMT1 Increases expression PMID:22016648
1267 CNP Decreases expression PMID:20233944
14325 FTL1 Increases expression PMID:22016648
14869 GSTP2 Decreases expression PMID:22016648
1544 CYP1A2 Increases activity PMID:16639589
1544 CYP1A2 Increases expression PMID:16639589
1571 CYP2E1 Decreases activity PMID:11330834; PMID:12814958; PMID:15306208
1588 CYP19A1 Decreases activity PMID:16480277
1588 CYP19A1 Decreases expression PMID:16480277
1649 DDIT3 Increases expression PMID:22016648
2052 EPHX1 Increases expression PMID:22016648
2167 FABP4 Increases expression PMID:22016648
22154 TUBB5 Increases expression PMID:22016648
2353 FOS Increases activity PMID:16169568
252969 NEIL2 Increases expression PMID:21145906
2806 GOT2 Increases expression PMID:21708182
293 SLC25A6 Increases expression PMID:22016648
302 ANXA2 Increases expression PMID:22016648
3094 HINT1 Increases expression PMID:22016648
328 APEX1 Increases activity PMID:23352893
328 APEX1 Increases expression PMID:23352893
3295 HSD17B4 Increases expression PMID:22016648
3303 HSPA1A Increases expression PMID:22016648
3326 HSP90AB1 Increases expression PMID:22016648
3420 IDH3B Increases expression PMID:22016648
3551 IKBKB Increases expression PMID:18420242
3552 IL1A Increases expression PMID:15694462; PMID:18420242
3569 IL6 Increases expression PMID:15694462; PMID:18420242
3576 CXCL8 Increases expression PMID:27965148
3725 JUN Increases activity PMID:16169568
3725 JUN Increases expression PMID:18420242
3816 KLK1 Decreases activity PMID:11151026
4171 MCM2 Increases expression PMID:21070798
4288 MKI67 Increases expression PMID:21070798
467 ATF3 Increases expression PMID:27965148
4792 NFKBIA Decreases expression PMID:18420242
4793 NFKBIB Decreases expression PMID:18420242
4843 NOS2 Increases expression PMID:21708182
4913 NTHL1 Increases activity PMID:23352893
4913 NTHL1 Increases expression PMID:23352893
4953 ODC1 Decreases expression PMID:22016648
5111 PCNA Affects expression PMID:21070798; PMID:22016648
595 CCND1 Increases expression PMID:21070798
5950 RBP4 Increases expression PMID:22016648
5970 RELA Increases activity PMID:15694462; PMID:18420242
5970 RELA Increases expression PMID:15694462; PMID:18420242
6647 SOD1 Increases expression PMID:22016648
6696 SPP1 Increases expression PMID:22016648
7040 TGFB1 Increases expression PMID:16169568
7078 TIMP3 Increases expression PMID:22016648
7124 TNF Increases expression PMID:15694462; PMID:18420242
79661 NEIL1 Increases expression PMID:21145906
890 CCNA2 Increases expression PMID:28463034
891 CCNB1 Increases expression PMID:28463034
894 CCND2 Increases expression PMID:21070798
896 CCND3 Increases expression PMID:21070798; PMID:28463034
898 CCNE1 Increases expression PMID:21070798; PMID:28463034
900 CCNG1 Increases expression PMID:22016648
983 CDK1 Increases expression PMID:28463034
993 CDC25A Increases expression PMID:28463034
DISCLAIMER

We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.