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Curated chemical-gene interactions from CTD
Entrez gene IDGene symbolInteraction typeReference
2539 G6PD Increases activity PMID:24911673
2641 GCG Decreases activity PMID:24911673
3553 IL1B Decreases expression PMID:16368379
4969 OGN Increases expression PMID:32513693
5593 PRKG2 Increases expression PMID:32513693
650 BMP2 Decreases expression PMID:32513693
7124 TNF Decreases expression PMID:16368379
8654 PDE5A Decreases activity PMID:15934858; PMID:16368379; PMID:17137605; PMID:17138653

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We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.