1,2-Dibromo-4-(1,2-dibromoethyl)cyclohexane


Curated chemical-gene interactions from CTD
Entrez gene IDGene symbolInteraction typeReference
14960 H2-AA Decreases expression PMID:31696622
14972 H2-K1 Decreases expression PMID:31696622
1583 CYP11A1 Increases expression PMID:29556062
1586 CYP17A1 Increases expression PMID:29556062
1728 NQO1 Increases expression PMID:31696622
22059 TRP53 Increases expression PMID:31696622
2346 FOLH1 Affects expression PMID:26729308
2876 GPX1 Increases expression PMID:31696622
2877 GPX2 Increases expression PMID:31696622
354 KLK3 Increases expression PMID:20049203; PMID:29556062; PMID:26729308; PMID:27473015; PMID:29556062
3553 IL1B Increases expression PMID:31696622
3569 IL6 Increases expression PMID:31696622
367 AR Increases activity PMID:17149866; PMID:20049203; PMID:20049203
367 AR Increases expression PMID:27473015
3936 LCP1 Increases expression PMID:27473015; PMID:29556062
4477 MSMB Increases expression PMID:27473015; PMID:29556062
581 BAX Increases expression PMID:31696622
6647 SOD1 Increases expression PMID:31696622
6648 SOD2 Increases expression PMID:31696622
6715 SRD5A1 Increases expression PMID:29556062
6770 STAR Increases expression PMID:29556062
7124 TNF Increases expression PMID:31696622
836 CASP3 Increases expression PMID:31696622
841 CASP8 Increases expression PMID:31696622
842 CASP9 Increases expression PMID:31696622
847 CAT Increases activity PMID:31696622
847 CAT Increases expression PMID:31696622
941 CD80 Decreases expression PMID:31696622
942 CD86 Decreases expression PMID:31696622
DISCLAIMER

We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.