Dibutyldichlorotin


Curated chemical-gene interactions from CTD
Entrez gene IDGene symbolInteraction typeReference
10808 HSPH1 Increases expression PMID:24356939
1103 CHAT Decreases activity PMID:9015740
11080 DNAJB4 Increases expression PMID:24356939
114548 NLRP3 Increases expression PMID:37169277
1277 COL1A1 Increases expression PMID:30611790; PMID:37169277
1588 CYP19A1 Decreases activity PMID:11522339
18811 PRL2C2 Increases expression PMID:10722888
1958 EGR1 Increases expression PMID:10722888
2167 FABP4 Increases expression PMID:37142754
2335 FN1 Increases expression PMID:30611790; PMID:30611790; PMID:37169277
2353 FOS Increases expression PMID:10722888
2354 FOSB Increases expression PMID:10722888
23657 SLC7A11 Increases expression PMID:24356939
3292 HSD17B1 Increases activity PMID:16513093
3297 HSF1 Increases activity PMID:34170685
3304 HSPA1B Increases expression PMID:24356939
3310 HSPA6 Increases expression PMID:24356939
3337 DNAJB1 Increases expression PMID:24356939
3606 IL18 Increases expression PMID:37169277
3725 JUN Increases expression PMID:10722888
3726 JUNB Increases expression PMID:10722888
4088 SMAD3 Increases expression PMID:30611790
4092 SMAD7 Decreases expression PMID:30611790
4313 MMP2 Increases expression PMID:30611790
4322 MMP13 Increases expression PMID:30611790
4502 MT2A Increases expression PMID:10722888
4609 MYC Increases expression PMID:10722888
4953 ODC1 Increases expression PMID:10722888
5468 PPARG Increases expression PMID:37142754
5594 MAPK1 Increases activity PMID:16181675
5595 MAPK3 Increases activity PMID:16181675
59 ACTA2 Increases expression PMID:30611790; PMID:37169277
6241 RRM2 Increases expression PMID:10722888
6347 CCL2 Increases expression PMID:10722888
63920 FAM200C Increases expression PMID:24356939
6647 SOD1 Increases expression PMID:10722888
6648 SOD2 Increases expression PMID:10722888
6715 SRD5A1 Decreases activity PMID:12231121
6716 SRD5A2 Decreases activity PMID:17218080
7040 TGFB1 Decreases activity PMID:31652400
7040 TGFB1 Increases expression PMID:30611790
7076 TIMP1 Increases expression PMID:30611790
7077 TIMP2 Increases expression PMID:30611790
81631 MAP1LC3B Increases expression PMID:30611790; PMID:37169277
834 CASP1 Increases expression PMID:37169277
8520 HAT1 Increases activity PMID:15603928
8678 BECN1 Increases expression PMID:30611790; PMID:37169277
8832 CD84 Increases expression PMID:24356939
8878 SQSTM1 Decreases expression PMID:30611790
9294 S1PR2 Increases expression PMID:37169277
9370 ADIPOQ Increases expression PMID:37142754
9474 ATG5 Increases expression PMID:30611790; PMID:37169277
DISCLAIMER

We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.