Malaoxon


Curated chemical-gene interactions from CTD
Entrez gene IDGene symbolInteraction typeReference
100506658 OCLN Decreases expression PMID:20970449
10908 PNPLA6 Decreases activity PMID:9268605
3162 HMOX1 Increases expression PMID:34778934
43 ACHE Decreases activity PMID:20406208; PMID:597376; PMID:9268605; PMID:9515941; PMID:21251949; PMID:21354413; PMID:27132127; PMID:33720374; PMID:4859365; PMID:8783813; PMID:9268605; PMID:9515941; PMID:21251949; PMID:33720374; PMID:30625376
5743 PTGS2 Increases expression PMID:30673264
596 BCL2 Increases expression PMID:30673264
5970 RELA Increases expression PMID:30673264
7082 TJP1 Decreases expression PMID:20970449
7122 CLDN5 Decreases expression PMID:20970449
7220 TRPC1 Increases expression PMID:22674931
7223 TRPC4 Increases expression PMID:22674931
847 CAT Decreases expression PMID:30673264
9414 TJP2 Decreases expression PMID:20970449

DISCLAIMER

We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.