2,3,7,8-Tetrabromodibenzo-4-dioxin


Curated chemical-gene interactions from CTD
Entrez gene IDGene symbolInteraction typeReference
10840 ALDH1L1 Increases expression PMID:27604104
11185 INMT Increases expression PMID:27604104
114787 GPRIN1 Increases expression PMID:27604104
11522 ADH1 Decreases expression PMID:27604104
1373 CPS1 Increases expression PMID:27604104
148811 PM20D1 Increases expression PMID:27604104
1491 CTH Increases expression PMID:27604104
1528 CYB5A Increases expression PMID:27604104
1543 CYP1A1 Increases activity PMID:27604104
1543 CYP1A1 Increases expression PMID:27604104
1544 CYP1A2 Increases activity PMID:27604104
1544 CYP1A2 Increases expression PMID:27604104
1583 CYP11A1 Decreases expression PMID:17447562
1585 CYP11B2 Increases expression PMID:17447562
1586 CYP17A1 Decreases expression PMID:17447562
1589 CYP21A2 Decreases expression PMID:17447562
1807 DPYS Increases expression PMID:27604104
191 AHCY Increases expression PMID:27604104
196 AHR Increases activity PMID:12850102; PMID:15099731; PMID:28669845
200014 CC2D1B Decreases expression PMID:27604104
2023 ENO1 Increases expression PMID:27604104
2053 EPHX2 Increases expression PMID:27604104
210 ALAD Increases expression PMID:27604104
217 ALDH2 Increases expression PMID:27604104
2203 FBP1 Increases expression PMID:27604104
229 ALDOB Decreases expression PMID:27604104
23498 HAAO Increases expression PMID:27604104
26061 HACL1 Increases expression PMID:27604104
27034 ACAD8 Increases expression PMID:27604104
2746 GLUD1 Increases expression PMID:27604104
2752 GLUL Decreases expression PMID:27604104
2805 GOT1 Affects expression PMID:27604104
2954 GSTZ1 Increases expression PMID:27604104
3242 HPD Increases expression PMID:27604104
3284 HSD3B2 Increases expression PMID:17447562
3295 HSD17B4 Decreases expression PMID:17447562
34 ACADM Decreases expression PMID:27604104
3567 IL5 Decreases expression PMID:19041680
383 ARG1 Increases expression PMID:27604104
4190 MDH1 Increases expression PMID:27604104
445 ASS1 Affects expression PMID:27604104
50 ACO2 Decreases expression PMID:27604104
501 ALDH7A1 Increases expression PMID:27604104
5052 PRDX1 Increases expression PMID:27604104
5091 PC Increases expression PMID:27604104
5095 PCCA Increases expression PMID:27604104
5160 PDHA1 Affects expression PMID:27604104
51726 DNAJB11 Increases expression PMID:27604104
5682 PSMA1 Increases expression PMID:27604104
5687 PSMA6 Increases expression PMID:27604104
593 BCKDHA Increases expression PMID:27604104
64087 MCCC2 Decreases expression PMID:27604104
64577 ALDH8A1 Increases expression PMID:27604104
6470 SHMT1 Increases expression PMID:27604104
6647 SOD1 Increases expression PMID:27604104
6652 SORD Increases expression PMID:27604104
7018 TF Increases expression PMID:27604104
847 CAT Decreases expression PMID:27604104
8659 ALDH4A1 Decreases expression PMID:27604104
9874 TLK1 Decreases expression PMID:27604104
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We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.