6-(1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)cyclopropyl)-3-pyridinecarboxylic acid


Curated chemical-gene interactions from CTD
Entrez gene IDGene symbolInteraction typeReference
1017 CDK2 Decreases expression PMID:15729575
1082 CGB3 Increases expression PMID:15941851
123 PLIN2 Increases expression PMID:16489205
1267 CNP Increases expression PMID:30027469
1524 CX3CR1 Decreases expression PMID:19850645
1588 CYP19A1 Affects activity PMID:10814527; PMID:15941851
1588 CYP19A1 Affects expression PMID:10814527; PMID:15941851
1733 DIO1 Increases activity PMID:16306084
1733 DIO1 Increases expression PMID:16306084
1734 DIO2 Decreases expression PMID:16306084
1734 DIO2 Increases activity PMID:16306084
20249 SCD1 Increases expression PMID:30027469
2494 NR5A2 Decreases expression PMID:16357189
3292 HSD17B1 Increases activity PMID:16513093
3292 HSD17B1 Increases expression PMID:16513093
336 APOA2 Increases expression PMID:8668150
3397 ID1 Increases expression PMID:17178900
3455 IFNAR2 Increases expression PMID:30027469
3489 IGFBP6 Increases expression PMID:17178900
3586 IL10 Increases expression PMID:30027469
3667 IRS1 Increases expression PMID:30027469
3827 KNG1 Increases expression PMID:30027469
4199 ME1 Increases expression PMID:16489205
51 ACOX1 Increases expression PMID:16489205
5468 PPARG Increases activity PMID:15729575
57834 CYP4F11 Increases expression PMID:19812349
5915 RARB Increases expression PMID:30027469
5916 RARG Increases expression PMID:30027469
5925 RB1 Decreases expression PMID:15729575
595 CCND1 Decreases expression PMID:16273314
6256 RXRA Increases activity PMID:12519787; PMID:15544927; PMID:15941851; PMID:16258897
6256 RXRA Increases expression PMID:15941851
6319 SCD Increases expression PMID:17178900
6770 STAR Increases expression PMID:23362264
7068 THRB Increases expression PMID:30027469
7252 TSHB Decreases expression PMID:16306084
890 CCNA2 Decreases expression PMID:15729575
891 CCNB1 Decreases expression PMID:15729575
896 CCND3 Decreases expression PMID:15729575
898 CCNE1 Decreases expression PMID:15729575
9970 NR1I3 Decreases expression PMID:30027469
9971 NR1H4 Decreases activity PMID:12519787
DISCLAIMER

We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.