Captafol


Curated chemical-gene interactions from CTD
Entrez gene IDGene symbolInteraction typeReference
1733 DIO1 Decreases activity PMID:29228274; PMID:30561685
1734 DIO2 Decreases activity PMID:30561685
1735 DIO3 Decreases activity PMID:30561685
2950 GSTP1 Decreases activity PMID:8678907
5111 PCNA Increases expression PMID:9022123
7031 TFF1 Decreases expression PMID:33352482
7150 TOP1 Decreases activity PMID:12113771
7153 TOP2A Decreases activity PMID:12113771

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We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.