Phtpp


Curated chemical-gene interactions from CTD
Entrez gene IDGene symbolInteraction typeReference
1588 CYP19A1 Increases expression PMID:30599193
2100 ESR2 Decreases activity PMID:24425189; PMID:25106122; PMID:27071941
2100 ESR2 Increases expression PMID:19270784
5532 PPP3CB Increases expression PMID:34023961

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We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.