Fenvalerate


Curated chemical-phenotype interactions from CTD
GO IDGO nameInteraction typeReference
GO:0001836 Release of cytochrome c from mitochondria Increases phenotype PMID:30307764
GO:0004035 Alkaline phosphatase activity Increases phenotype PMID:33396045; PMID:35678313
GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity Increases phenotype PMID:33396045; PMID:35678313
GO:0004096 Catalase activity Affects phenotype PMID:33396045
GO:0004303 Estradiol 17-beta-dehydrogenase activity Decreases phenotype PMID:34896426
GO:0004364 Glutathione transferase activity Increases phenotype PMID:33396045
GO:0004457 Lactate dehydrogenase activity Affects phenotype PMID:35678313
GO:0004602 Glutathione peroxidase activity Increases phenotype PMID:33396045; PMID:35678313; PMID:35678313
GO:0004784 Superoxide dismutase activity Increases phenotype PMID:35678313
GO:0006497 Protein lipidation Increases phenotype PMID:31734597
GO:0006641 Triglyceride metabolic process Affects phenotype PMID:30307764; PMID:33396045; PMID:33396045; PMID:35678313; PMID:35678313
GO:0006874 Cellular calcium ion homeostasis Increases phenotype PMID:30307764; PMID:34748853
GO:0006915 Apoptotic process Increases phenotype PMID:28949029; PMID:30307764
GO:0006997 Nucleus organization Decreases phenotype PMID:28949029
GO:0007283 Spermatogenesis Decreases phenotype PMID:31524104; PMID:33656234; PMID:34896426
GO:0007340 Acrosome reaction Decreases phenotype PMID:33396045; PMID:34896426
GO:0007612 Learning Affects phenotype PMID:32693020
GO:0007613 Memory Affects phenotype PMID:32693020; PMID:34358930
GO:0007623 Circadian rhythm Affects phenotype PMID:29040059
GO:0008203 Cholesterol metabolic process Affects phenotype PMID:35678313
GO:0008219 Cell death Increases phenotype PMID:26961610
GO:0008283 Cell population proliferation Affects phenotype PMID:16326432; PMID:32693020
GO:0008542 Visual learning Affects phenotype PMID:34358930
GO:0016042 Lipid catabolic process Affects phenotype PMID:30307764; PMID:33396045; PMID:33396045; PMID:35678313; PMID:35678313
GO:0022008 Neurogenesis Decreases phenotype PMID:34358930
GO:0030263 Apoptotic chromosome condensation Increases phenotype PMID:32693020
GO:0030283 Testosterone dehydrogenase [nad(p)] activity Decreases phenotype PMID:33396045
GO:0031959 Mineralocorticoid receptor signaling pathway Increases phenotype PMID:29149346
GO:0033148 Positive regulation of intracellular estrogen receptor signaling pathway Increases phenotype PMID:25449125
GO:0036126 Sperm flagellum Affects phenotype PMID:33656234
GO:0042417 Dopamine metabolic process Affects phenotype PMID:31734597
GO:0043065 Positive regulation of apoptotic process Increases phenotype PMID:31524104
GO:0044237 Cellular metabolic process Decreases phenotype PMID:28949029; PMID:34748853
GO:0046209 Nitric oxide metabolic process Affects phenotype PMID:35678313
GO:0048240 Sperm capacitation Decreases phenotype PMID:33396045; PMID:34896426
GO:0051090 Regulation of dna-binding transcription factor activity Affects phenotype PMID:28369636
GO:0051882 Mitochondrial depolarization Increases phenotype PMID:30307764
GO:0055074 Calcium ion homeostasis Affects phenotype PMID:29040059
GO:0060716 Labyrinthine layer blood vessel development Affects phenotype PMID:28369636
GO:0061370 Testosterone biosynthetic process Decreases phenotype PMID:29040059; PMID:34896426; PMID:36053783
GO:0070265 Necrotic cell death Increases phenotype PMID:28949029; PMID:30307764
GO:0071466 Cellular response to xenobiotic stimulus Increases phenotype PMID:26921727
GO:0072593 Reactive oxygen species metabolic process Affects phenotype PMID:30307764; PMID:34748853
GO:0102727 3beta-hydroxysteroid dehydrogenase activity Decreases phenotype PMID:33396045; PMID:34896426; PMID:36053783
GO:1901522 Positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus Increases phenotype PMID:26921727
GO:2000027 Regulation of animal organ morphogenesis Decreases phenotype PMID:31524104
GO:2000844 Negative regulation of testosterone secretion Increases phenotype PMID:31524104
DISCLAIMER

We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.