Acetaldehyde


Curated chemical-phenotype interactions from CTD
GO IDGO nameInteraction typeReference
GO:0000266 Mitochondrial fission Affects phenotype PMID:35158046
GO:0001649 Osteoblast differentiation Decreases phenotype PMID:28017615
GO:0004030 Aldehyde dehydrogenase [nad(p)+] activity Decreases phenotype PMID:35158046
GO:0004035 Alkaline phosphatase activity Decreases phenotype PMID:28017615
GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity Increases phenotype PMID:35158046
GO:0005739 Mitochondrion Increases phenotype PMID:35158046
GO:0006117 Acetaldehyde metabolic process Affects phenotype PMID:30255327; PMID:34830855; PMID:39988212
GO:0006749 Glutathione metabolic process Increases phenotype PMID:35595033
GO:0006750 Glutathione biosynthetic process Decreases phenotype PMID:28017615
GO:0006915 Apoptotic process Increases phenotype PMID:35158046
GO:0008285 Negative regulation of cell population proliferation Increases phenotype PMID:35595033
GO:0010942 Positive regulation of cell death Increases phenotype PMID:28821405
GO:0014063 Negative regulation of serotonin secretion Increases phenotype PMID:26711020
GO:0016042 Lipid catabolic process Increases phenotype PMID:28017615; PMID:35158046
GO:0032125 Micronucleus organization Increases phenotype PMID:29110037
GO:0033602 Negative regulation of dopamine secretion Increases phenotype PMID:26711020
GO:0034440 Lipid oxidation Increases phenotype PMID:35595033
GO:0036211 Protein modification process Increases phenotype PMID:28119953
GO:0042310 Vasoconstriction Increases phenotype PMID:2727987
GO:0044237 Cellular metabolic process Decreases phenotype PMID:35158046
GO:0045930 Negative regulation of mitotic cell cycle Increases phenotype PMID:29110037
GO:0046034 Atp metabolic process Affects phenotype PMID:35158046
GO:0051560 Mitochondrial calcium ion homeostasis Affects phenotype PMID:35158046
GO:0051881 Regulation of mitochondrial membrane potential Affects phenotype PMID:35158046
GO:0055072 Iron ion homeostasis Decreases phenotype PMID:35595033
GO:0070994 Detection of oxidative stress Increases phenotype PMID:28017615
GO:0072593 Reactive oxygen species metabolic process Affects phenotype PMID:35158046
GO:0150032 Positive regulation of protein localization to lysosome Increases phenotype PMID:35595033
GO:0160020 Positive regulation of ferroptosis Increases phenotype PMID:35595033
GO:1901525 Negative regulation of mitophagy Increases phenotype PMID:35595033
GO:1903428 Positive regulation of reactive oxygen species biosynthetic process Increases phenotype PMID:35595033
GO:2000786 Positive regulation of autophagosome assembly Increases phenotype PMID:35595033
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We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.