Iodine


Curated chemical-phenotype interactions from CTD
GO IDGO nameInteraction typeReference
GO:0002523 Leukocyte migration involved in inflammatory response Increases phenotype PMID:37598415
GO:0003429 Growth plate cartilage chondrocyte morphogenesis Decreases phenotype PMID:38060174
GO:0003432 Cell growth involved in growth plate cartilage chondrocyte morphogenesis Decreases phenotype PMID:38060174
GO:0008203 Cholesterol metabolic process Affects phenotype PMID:23517243
GO:0008219 Cell death Increases phenotype PMID:14500569
GO:0009636 Response to toxic substance Increases phenotype PMID:30090431
GO:0015705 Iodide transport Decreases phenotype PMID:30352396
GO:0021884 Forebrain neuron development Decreases phenotype PMID:22987596
GO:0040015 Negative regulation of multicellular organism growth Increases phenotype PMID:30090431
GO:0042403 Thyroid hormone metabolic process Affects phenotype PMID:26517287
GO:0046621 Negative regulation of organ growth Increases phenotype PMID:30090431
GO:0046676 Negative regulation of insulin secretion Increases phenotype PMID:30090431
GO:0070276 Halogen metabolic process Affects phenotype PMID:28054989
GO:0097484 Dendrite extension Decreases phenotype PMID:27444543
GO:1902731 Negative regulation of chondrocyte proliferation Decreases phenotype PMID:38060174
GO:1904214 Positive regulation of iodide transmembrane transport Increases phenotype PMID:22982218
GO:2000609 Regulation of thyroid hormone generation Affects phenotype PMID:29385629
GO:2000610 Negative regulation of thyroid hormone generation Increases phenotype PMID:30090431
GO:2000614 Positive regulation of thyroid-stimulating hormone secretion Increases phenotype PMID:26517287; PMID:38060174
GO:2000854 Positive regulation of corticosterone secretion Increases phenotype PMID:30090431
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We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.