Methylbenzene


Curated chemical-phenotype interactions from CTD
GO IDGO nameInteraction typeReference
GO:0000723 Telomere maintenance Decreases phenotype PMID:19772576
GO:0001508 Action potential Affects phenotype PMID:32234516
GO:0001776 Leukocyte homeostasis Affects phenotype PMID:31988427
GO:0005245 Voltage-gated calcium channel activity Decreases phenotype PMID:29925288
GO:0005248 Voltage-gated sodium channel activity Affects phenotype PMID:29925288
GO:0006750 Glutathione biosynthetic process Decreases phenotype PMID:24733833
GO:0006809 Nitric oxide biosynthetic process Increases phenotype PMID:24733833
GO:0007088 Regulation of mitotic nuclear division Decreases phenotype PMID:23138419
GO:0007271 Synaptic transmission, cholinergic Affects phenotype PMID:30097702
GO:0007613 Memory Decreases phenotype PMID:29935984; PMID:29935984; PMID:32980479; PMID:33086094; PMID:32234516; PMID:32980479; PMID:33086094
GO:0008344 Adult locomotory behavior Affects phenotype PMID:29935984
GO:0010424 Dna methylation on cytosine within a cg sequence Affects phenotype PMID:33438815
GO:0010460 Positive regulation of heart rate Increases phenotype PMID:29925288
GO:0023041 Neuronal signal transduction Affects phenotype PMID:32980479
GO:0030097 Hemopoiesis Affects phenotype PMID:31988427
GO:0030220 Platelet formation Affects phenotype PMID:31988427
GO:0035176 Social behavior Decreases phenotype PMID:29935984; PMID:29935984; PMID:33086094; PMID:32980479; PMID:33086094
GO:0035249 Synaptic transmission, glutamatergic Affects phenotype PMID:30097702
GO:0035934 Corticosterone secretion Increases phenotype PMID:37944760
GO:0042403 Thyroid hormone metabolic process Increases phenotype PMID:37944760
GO:0048167 Regulation of synaptic plasticity Affects phenotype PMID:30097702
GO:0050879 Multicellular organismal movement Increases phenotype PMID:32980479
GO:0060291 Long-term synaptic potentiation Decreases phenotype PMID:33086094
GO:0061900 Glial cell activation Increases phenotype PMID:32234516
GO:0090648 Response to environmental enrichment Decreases phenotype PMID:33086094
GO:0098989 Nmda selective glutamate receptor signaling pathway Affects phenotype PMID:30097702
GO:0099565 Chemical synaptic transmission, postsynaptic Affects phenotype PMID:33086094
GO:1900996 Benzene catabolic process Decreases phenotype PMID:30086327
GO:2000310 Regulation of nmda receptor activity Affects phenotype PMID:30097702

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We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.