Carbofuran


Curated chemical-phenotype interactions from CTD
GO IDGO nameInteraction typeReference
GO:0000212 Meiotic spindle organization Decreases phenotype PMID:25564422
GO:0002052 Positive regulation of neuroblast proliferation Decreases phenotype PMID:28982980
GO:0002693 Positive regulation of cellular extravasation Increases phenotype PMID:34264070
GO:0004035 Alkaline phosphatase activity Increases phenotype PMID:19778259; PMID:31334637; PMID:31696704
GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity Increases phenotype PMID:31334637; PMID:31696704
GO:0004346 Glucose-6-phosphatase activity Increases phenotype PMID:19778259
GO:0004364 Glutathione transferase activity Decreases phenotype PMID:24865641
GO:0004457 Lactate dehydrogenase activity Increases phenotype PMID:19778259; PMID:31334637; PMID:31696704
GO:0004575 Sucrose alpha-glucosidase activity Increases phenotype PMID:19778259
GO:0004602 Glutathione peroxidase activity Decreases phenotype PMID:31334637; PMID:31696704
GO:0004784 Superoxide dismutase activity Decreases phenotype PMID:24865641; PMID:31334637; PMID:31696704; PMID:31696704
GO:0005391 P-type sodium:potassium-exchanging transporter activity Decreases phenotype PMID:24865641
GO:0007132 Meiotic metaphase i Decreases phenotype PMID:25564422
GO:0008284 Positive regulation of cell population proliferation Affects phenotype PMID:28982980; PMID:33629750
GO:0010918 Positive regulation of mitochondrial membrane potential Increases phenotype PMID:33629750
GO:0010942 Positive regulation of cell death Increases phenotype PMID:28725974
GO:0010972 Negative regulation of g2/m transition of mitotic cell cycle Increases phenotype PMID:33629750
GO:0015723 Bilirubin transport Increases phenotype PMID:34264070
GO:0016042 Lipid catabolic process Increases phenotype PMID:31334637; PMID:31696704
GO:0016325 Oocyte microtubule cytoskeleton organization Decreases phenotype PMID:25564422
GO:0019432 Triglyceride biosynthetic process Increases phenotype PMID:31334637; PMID:31334637; PMID:31696704
GO:0021953 Central nervous system neuron differentiation Decreases phenotype PMID:28982980
GO:0022010 Central nervous system myelination Decreases phenotype PMID:30471306
GO:0030511 Positive regulation of transforming growth factor beta receptor signaling pathway Increases phenotype PMID:28982980
GO:0034440 Lipid oxidation Increases phenotype PMID:34264070
GO:0040015 Negative regulation of multicellular organism growth Increases phenotype PMID:34264070
GO:0042755 Eating behavior Decreases phenotype PMID:31334637
GO:0042756 Drinking behavior Decreases phenotype PMID:31334637
GO:0043065 Positive regulation of apoptotic process Increases phenotype PMID:28982980; PMID:33629750
GO:0043687 Post-translational protein modification Increases phenotype PMID:27657490
GO:0045792 Negative regulation of cell size Increases phenotype PMID:34264070
GO:0045793 Positive regulation of cell size Increases phenotype PMID:34264070
GO:0048711 Positive regulation of astrocyte differentiation Increases phenotype PMID:28982980; PMID:30471306
GO:0048715 Negative regulation of oligodendrocyte differentiation Increases phenotype PMID:30471306
GO:0050671 Positive regulation of lymphocyte proliferation Increases phenotype PMID:34264070
GO:0051881 Regulation of mitochondrial membrane potential Affects phenotype PMID:37046073
GO:0060322 Head development Decreases phenotype PMID:19900697
GO:0060631 Regulation of meiosis i Affects phenotype PMID:25564422
GO:0061516 Monocyte proliferation Increases phenotype PMID:34264070
GO:0070328 Triglyceride homeostasis Decreases phenotype PMID:34264070
GO:0070446 Negative regulation of oligodendrocyte progenitor proliferation Increases phenotype PMID:30471306
GO:0070447 Positive regulation of oligodendrocyte progenitor proliferation Decreases phenotype PMID:28982980
GO:0070994 Detection of oxidative stress Increases phenotype PMID:24865641
GO:0098727 Maintenance of cell number Decreases phenotype PMID:34264070
GO:1900143 Positive regulation of oligodendrocyte apoptotic process Increases phenotype PMID:30471306
GO:1901318 Negative regulation of flagellated sperm motility Increases phenotype PMID:8847449
GO:1901670 Negative regulation of superoxide dismutase activity Increases phenotype PMID:34264070
GO:1902157 Regulation of response to g2 dna damage checkpoint signaling Affects phenotype PMID:33629750
GO:1903283 Negative regulation of glutathione peroxidase activity Increases phenotype PMID:34264070
GO:1903428 Positive regulation of reactive oxygen species biosynthetic process Increases phenotype PMID:33629750
GO:1905220 Negative regulation of platelet formation Increases phenotype PMID:34264070
GO:1905665 Positive regulation of calcium ion import across plasma membrane Increases phenotype PMID:28725974
GO:2001272 Positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis Increases phenotype PMID:25564422
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We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.