Patulin


Curated chemical-phenotype interactions from CTD
GO IDGO nameInteraction typeReference
GO:0001556 Oocyte maturation Decreases phenotype PMID:34718031
GO:0004602 Glutathione peroxidase activity Decreases phenotype PMID:33577942; PMID:35772596
GO:0004784 Superoxide dismutase activity Affects phenotype PMID:26095701; PMID:33577942
GO:0006534 Cysteine metabolic process Affects phenotype PMID:35772596
GO:0006749 Glutathione metabolic process Affects phenotype PMID:26584762; PMID:33577942; PMID:35772596
GO:0006750 Glutathione biosynthetic process Increases phenotype PMID:30266311
GO:0006884 Cell volume homeostasis Affects phenotype PMID:33217525
GO:0006915 Apoptotic process Increases phenotype PMID:26095701; PMID:33577942
GO:0007009 Plasma membrane organization Affects phenotype PMID:33217525
GO:0007057 Spindle assembly involved in female meiosis i Decreases phenotype PMID:34718031
GO:0008219 Cell death Increases phenotype PMID:27913847; PMID:27913847; PMID:29604266; PMID:29604266; PMID:35772596
GO:0008283 Cell population proliferation Decreases phenotype PMID:27913847
GO:0015811 L-cystine transport Affects phenotype PMID:35772596
GO:0016042 Lipid catabolic process Increases phenotype PMID:26095701
GO:0016567 Protein ubiquitination Affects phenotype PMID:35367319
GO:0018158 Protein oxidation Increases phenotype PMID:26095701; PMID:26584762
GO:0030199 Collagen fibril organization Increases phenotype PMID:34896196
GO:0031619 Homologous chromosome orientation involved in meiotic metaphase i plate congression Affects phenotype PMID:34718031
GO:0032776 Dna methylation on cytosine Affects phenotype PMID:38806716
GO:0033566 Gamma-tubulin complex localization Affects phenotype PMID:34718031
GO:0034440 Lipid oxidation Increases phenotype PMID:26584762; PMID:35772596
GO:0034976 Response to endoplasmic reticulum stress Increases phenotype PMID:25577197
GO:0042554 Superoxide anion generation Affects phenotype PMID:34896196
GO:0044237 Cellular metabolic process Decreases phenotype PMID:33577942; PMID:33577942; PMID:35772596; PMID:35367319; PMID:35772596
GO:0045454 Cell redox homeostasis Decreases phenotype PMID:26584762
GO:0046034 Atp metabolic process Increases phenotype PMID:33577942
GO:0050000 Chromosome localization Affects phenotype PMID:34718031
GO:0051881 Regulation of mitochondrial membrane potential Affects phenotype PMID:29604266; PMID:33577942; PMID:34718031
GO:0055072 Iron ion homeostasis Affects phenotype PMID:35772596
GO:0070269 Pyroptosis Increases phenotype PMID:33217525
GO:0070842 Aggresome assembly Affects phenotype PMID:35367319
GO:0070994 Detection of oxidative stress Increases phenotype PMID:35772596
GO:0072593 Reactive oxygen species metabolic process Affects phenotype PMID:33577942; PMID:34718031; PMID:34896196; PMID:35772596
GO:0097212 Lysosomal membrane organization Affects phenotype PMID:33217525
GO:1901671 Positive regulation of superoxide dismutase activity Increases phenotype PMID:26584762
GO:1902177 Positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway Increases phenotype PMID:25577197
GO:1902237 Positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway Increases phenotype PMID:25577197
GO:1903409 Reactive oxygen species biosynthetic process Increases phenotype PMID:29604266
DISCLAIMER

We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.