Chlordane


Curated chemical-phenotype interactions from CTD
GO IDGO nameInteraction typeReference
GO:0005249 Voltage-gated potassium channel activity Decreases phenotype PMID:36511510
GO:0006007 Glucose catabolic process Increases phenotype PMID:31704469
GO:0006304 Dna modification Decreases phenotype PMID:28659405
GO:0006898 Receptor-mediated endocytosis Increases phenotype PMID:29329451
GO:0007173 Epidermal growth factor receptor signaling pathway Increases phenotype PMID:29329451
GO:0008283 Cell population proliferation Decreases phenotype PMID:31704469
GO:0019249 Lactate biosynthetic process Increases phenotype PMID:31704469
GO:0019835 Cytolysis Increases phenotype PMID:31704469
GO:0032148 Activation of protein kinase b activity Increases phenotype PMID:35137321
GO:0033148 Positive regulation of intracellular estrogen receptor signaling pathway Increases phenotype PMID:26022396
GO:0033993 Response to lipid Decreases phenotype PMID:28659405
GO:0035176 Social behavior Decreases phenotype PMID:35137321
GO:0040015 Negative regulation of multicellular organism growth Increases phenotype PMID:35137321
GO:0042554 Superoxide anion generation Affects phenotype PMID:31923579
GO:0042866 Pyruvate biosynthetic process Increases phenotype PMID:31704469
GO:0043433 Negative regulation of dna-binding transcription factor activity Increases phenotype PMID:26022396
GO:0044237 Cellular metabolic process Decreases phenotype PMID:31704469; PMID:36511510
GO:0045727 Positive regulation of translation Increases phenotype PMID:35137321
GO:0046323 Glucose import Affects phenotype PMID:31923579
GO:0050679 Positive regulation of epithelial cell proliferation Decreases phenotype PMID:28659405
GO:0050847 Progesterone receptor signaling pathway Decreases phenotype PMID:26022396
GO:0051602 Response to electrical stimulus Affects phenotype PMID:35137321
GO:0060075 Regulation of resting membrane potential Affects phenotype PMID:36511510
GO:0070374 Positive regulation of erk1 and erk2 cascade Increases phenotype PMID:29329451
GO:0072593 Reactive oxygen species metabolic process Affects phenotype PMID:31923579
GO:0090394 Negative regulation of excitatory postsynaptic potential Affects phenotype PMID:35137321
GO:0098781 Ncrna transcription Increases phenotype PMID:28541575
GO:0098900 Regulation of action potential Affects phenotype PMID:36511510
GO:0098990 Ampa selective glutamate receptor signaling pathway Affects phenotype PMID:35137321
GO:1900454 Positive regulation of long-term synaptic depression Affects phenotype PMID:35137321
GO:2001057 Reactive nitrogen species metabolic process Affects phenotype PMID:31923579
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We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.