| GO ID | GO name | Interaction type | Reference |
|---|---|---|---|
| GO:0002523 | Leukocyte migration involved in inflammatory response | Increases phenotype | PMID:26199281 |
| GO:0003854 | 3-beta-hydroxy-delta5-steroid dehydrogenase activity | Decreases phenotype | PMID:20521886 |
| GO:0004303 | Estradiol 17-beta-dehydrogenase activity | Decreases phenotype | PMID:20521886 |
| GO:0004364 | Glutathione transferase activity | Decreases phenotype | PMID:31797688 |
| GO:0004602 | Glutathione peroxidase activity | Decreases phenotype | PMID:20521886; PMID:31797688 |
| GO:0004784 | Superoxide dismutase activity | Decreases phenotype | PMID:20521886 |
| GO:0006749 | Glutathione metabolic process | Affects phenotype | PMID:31797688 |
| GO:0007283 | Spermatogenesis | Affects phenotype | PMID:20521886; PMID:2128298; PMID:3928886 |
| GO:0008217 | Regulation of blood pressure | Increases phenotype | PMID:1568764 |
| GO:0008283 | Cell population proliferation | Increases phenotype | PMID:35598691 |
| GO:0030850 | Prostate gland development | Increases phenotype | PMID:39495161 |
| GO:0033574 | Response to testosterone | Decreases phenotype | PMID:29778459 |
| GO:0034440 | Lipid oxidation | Increases phenotype | PMID:20521886; PMID:31797688 |
| GO:0046466 | Membrane lipid catabolic process | Increases phenotype | PMID:9430440 |
| GO:0046620 | Regulation of organ growth | Affects phenotype | PMID:2128298; PMID:3928886 |
| GO:0046660 | Female sex differentiation | Decreases phenotype | PMID:18340380 |
| GO:0046661 | Male sex differentiation | Increases phenotype | PMID:18340380 |
| GO:0048808 | Male genitalia morphogenesis | Increases phenotype | PMID:20002220 |
| GO:0061107 | Seminal vesicle development | Increases phenotype | PMID:39495161 |
| GO:0061370 | Testosterone biosynthetic process | Affects phenotype | PMID:20521886 |
| GO:0061951 | Establishment of protein localization to plasma membrane | Increases phenotype | PMID:30591588 |
| GO:2000610 | Negative regulation of thyroid hormone generation | Increases phenotype | PMID:29501854 |
We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.