| GO ID | GO name | Interaction type | Reference |
|---|---|---|---|
| GO:0006306 | Dna methylation | Increases phenotype | PMID:33865946 |
| GO:0006701 | Progesterone biosynthetic process | Decreases phenotype | PMID:27665777 |
| GO:0006750 | Glutathione biosynthetic process | Decreases phenotype | PMID:27214522 |
| GO:0006874 | Cellular calcium ion homeostasis | Affects phenotype | PMID:26187449 |
| GO:0006915 | Apoptotic process | Affects phenotype | PMID:27296064; PMID:27829164 |
| GO:0006997 | Nucleus organization | Decreases phenotype | PMID:27296064 |
| GO:0007596 | Blood coagulation | Decreases phenotype | PMID:27214522 |
| GO:0008283 | Cell population proliferation | Decreases phenotype | PMID:27214522; PMID:27829164 |
| GO:0008285 | Negative regulation of cell population proliferation | Increases phenotype | PMID:32949729 |
| GO:0010942 | Positive regulation of cell death | Increases phenotype | PMID:20654549 |
| GO:0019226 | Transmission of nerve impulse | Decreases phenotype | PMID:38599286 |
| GO:0022602 | Ovulation cycle process | Affects phenotype | PMID:27665777 |
| GO:0030220 | Platelet formation | Decreases phenotype | PMID:27214522 |
| GO:0044849 | Estrous cycle | Decreases phenotype | PMID:27665777 |
| GO:0046034 | Atp metabolic process | Affects phenotype | PMID:32949729 |
| GO:0051091 | Positive regulation of dna-binding transcription factor activity | Increases phenotype | PMID:28973306 |
| GO:1901386 | Negative regulation of voltage-gated calcium channel activity | Increases phenotype | PMID:26187449 |
We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.