| GO ID | GO name | Interaction type | Reference |
|---|---|---|---|
| GO:0006123 | Mitochondrial electron transport, cytochrome c to oxygen | Decreases phenotype | PMID:25421967 |
| GO:0006650 | Glycerophospholipid metabolic process | Decreases phenotype | PMID:38604439 |
| GO:0006749 | Glutathione metabolic process | Affects phenotype | PMID:32679257 |
| GO:0009449 | Gamma-aminobutyric acid biosynthetic process | Decreases phenotype | PMID:38604439 |
| GO:0010918 | Positive regulation of mitochondrial membrane potential | Decreases phenotype | PMID:25421967 |
| GO:0014053 | Negative regulation of gamma-aminobutyric acid secretion | Increases phenotype | PMID:38604439 |
| GO:0014063 | Negative regulation of serotonin secretion | Increases phenotype | PMID:38604439 |
| GO:0018158 | Protein oxidation | Affects phenotype | PMID:32679257 |
| GO:0043065 | Positive regulation of apoptotic process | Increases phenotype | PMID:25421967; PMID:38604439 |
| GO:0044237 | Cellular metabolic process | Affects phenotype | PMID:32679257 |
| GO:0072660 | Maintenance of protein location in plasma membrane | Affects phenotype | PMID:29320738 |
| GO:0090200 | Positive regulation of release of cytochrome c from mitochondria | Increases phenotype | PMID:25421967 |
| GO:1903428 | Positive regulation of reactive oxygen species biosynthetic process | Increases phenotype | PMID:25421967 |
| GO:1905628 | Negative regulation of serotonin biosynthetic process | Increases phenotype | PMID:38604439 |
| GO:2001024 | Negative regulation of response to drug | Increases phenotype | PMID:38604439 |
We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.