Dieldrin


Curated chemical-phenotype interactions from CTD
GO IDGO nameInteraction typeReference
GO:0004030 Aldehyde dehydrogenase [nad(p)+] activity Decreases phenotype PMID:24491970
GO:0004668 Protein-arginine deiminase activity Increases phenotype PMID:31068361
GO:0006260 Dna replication Increases phenotype PMID:32435917
GO:0006306 Dna methylation Affects phenotype PMID:38995845
GO:0007009 Plasma membrane organization Decreases phenotype PMID:28774849
GO:0007204 Positive regulation of cytosolic calcium ion concentration Increases phenotype PMID:28774849
GO:0008219 Cell death Increases phenotype PMID:28844784
GO:0008283 Cell population proliferation Affects phenotype PMID:22634143; PMID:9537283
GO:0008284 Positive regulation of cell population proliferation Decreases phenotype PMID:27816694
GO:0008285 Negative regulation of cell population proliferation Increases phenotype PMID:32949729
GO:0009299 Mrna transcription Affects phenotype PMID:31068361
GO:0010424 Dna methylation on cytosine within a cg sequence Affects phenotype PMID:30859219
GO:0010976 Positive regulation of neuron projection development Increases phenotype PMID:28385489
GO:0019226 Transmission of nerve impulse Affects phenotype PMID:38599286
GO:0031325 Positive regulation of cellular metabolic process Increases phenotype PMID:28774849
GO:0032148 Activation of protein kinase b activity Increases phenotype PMID:31068361
GO:0032776 Dna methylation on cytosine Affects phenotype PMID:38995845
GO:0033148 Positive regulation of intracellular estrogen receptor signaling pathway Increases phenotype PMID:26022396
GO:0040029 Epigenetic regulation of gene expression Affects phenotype PMID:38995845
GO:0043408 Regulation of mapk cascade Increases phenotype PMID:31068361
GO:0043433 Negative regulation of dna-binding transcription factor activity Increases phenotype PMID:26022396
GO:0045666 Positive regulation of neuron differentiation Decreases phenotype PMID:27816694
GO:0045687 Positive regulation of glial cell differentiation Increases phenotype PMID:27816694
GO:0045727 Positive regulation of translation Increases phenotype PMID:35137321
GO:0045893 Positive regulation of dna-templated transcription Increases phenotype PMID:30639747
GO:0046034 Atp metabolic process Affects phenotype PMID:32949729
GO:0048589 Developmental growth Increases phenotype PMID:31708466
GO:0050847 Progesterone receptor signaling pathway Decreases phenotype PMID:26022396
GO:0051345 Positive regulation of hydrolase activity Increases phenotype PMID:31068361
GO:0061527 Dopamine secretion, neurotransmission Increases phenotype PMID:37607008
GO:0071629 Cytoplasm protein quality control by the ubiquitin-proteasome system Decreases phenotype PMID:23988235
GO:0098781 Ncrna transcription Increases phenotype PMID:31068361
GO:0120187 Positive regulation of protein localization to chromatin Increases phenotype PMID:31068361
GO:1903409 Reactive oxygen species biosynthetic process Increases phenotype PMID:30240590
GO:1903428 Positive regulation of reactive oxygen species biosynthetic process Increases phenotype PMID:34051100
DISCLAIMER

We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.