Perchlorate


Curated chemical-phenotype interactions from CTD
GO IDGO nameInteraction typeReference
GO:0002260 Lymphocyte homeostasis Affects phenotype PMID:25673971
GO:0006590 Thyroid hormone generation Decreases phenotype PMID:30991129
GO:0006750 Glutathione biosynthetic process Decreases phenotype PMID:30991129
GO:0006915 Apoptotic process Increases phenotype PMID:11834455
GO:0006974 Cellular response to dna damage stimulus Increases phenotype PMID:30991129
GO:0016042 Lipid catabolic process Increases phenotype PMID:30991129
GO:0034101 Erythrocyte homeostasis Affects phenotype PMID:25673971
GO:0046879 Hormone secretion Increases phenotype PMID:20439182
GO:0048589 Developmental growth Decreases phenotype PMID:26151950
GO:0055072 Iron ion homeostasis Affects phenotype PMID:25673971
GO:0070460 Thyroid-stimulating hormone secretion Increases phenotype PMID:20439182; PMID:26408806
GO:2000609 Regulation of thyroid hormone generation Affects phenotype PMID:26485730
GO:2000610 Negative regulation of thyroid hormone generation Increases phenotype PMID:35385113

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We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.