Boric acid


Curated chemical-phenotype interactions from CTD
GO IDGO nameInteraction typeReference
GO:0001649 Osteoblast differentiation Affects phenotype PMID:24704097
GO:0002040 Sprouting angiogenesis Decreases phenotype PMID:27206737
GO:0002924 Negative regulation of humoral immune response mediated by circulating immunoglobulin Increases phenotype PMID:32179172
GO:0004784 Superoxide dismutase activity Decreases phenotype PMID:30997025
GO:0006094 Gluconeogenesis Increases phenotype PMID:30997025
GO:0006304 Dna modification Increases phenotype PMID:38108610
GO:0006695 Cholesterol biosynthetic process Increases phenotype PMID:30997025
GO:0006749 Glutathione metabolic process Increases phenotype PMID:26184899; PMID:29913234; PMID:31823256; PMID:38108610
GO:0006750 Glutathione biosynthetic process Decreases phenotype PMID:30997025
GO:0006809 Nitric oxide biosynthetic process Increases phenotype PMID:27206737
GO:0006879 Cellular iron ion homeostasis Affects phenotype PMID:38108610
GO:0006915 Apoptotic process Increases phenotype PMID:33137424; PMID:34175401
GO:0008283 Cell population proliferation Affects phenotype PMID:27206737; PMID:34175401
GO:0008284 Positive regulation of cell population proliferation Affects phenotype PMID:27587023; PMID:28285642; PMID:31368021
GO:0010884 Positive regulation of lipid storage Increases phenotype PMID:28285642
GO:0010890 Positive regulation of sequestering of triglyceride Decreases phenotype PMID:28285642
GO:0016042 Lipid catabolic process Increases phenotype PMID:30997025; PMID:31823256
GO:0019432 Triglyceride biosynthetic process Increases phenotype PMID:30997025
GO:0032024 Positive regulation of insulin secretion Increases phenotype PMID:31368021
GO:0032148 Activation of protein kinase b activity Increases phenotype PMID:28285642
GO:0032753 Positive regulation of interleukin-4 production Increases phenotype PMID:32179172
GO:0034063 Stress granule assembly Increases phenotype PMID:25425213
GO:0034440 Lipid oxidation Increases phenotype PMID:26184899; PMID:29913234; PMID:38108610
GO:0034976 Response to endoplasmic reticulum stress Increases phenotype PMID:25425213
GO:0035148 Tube formation Decreases phenotype PMID:27206737
GO:0042307 Positive regulation of protein import into nucleus Increases phenotype PMID:27587023
GO:0042593 Glucose homeostasis Decreases phenotype PMID:29913234; PMID:30368975
GO:0042632 Cholesterol homeostasis Decreases phenotype PMID:29913234; PMID:30368975
GO:0042692 Muscle cell differentiation Increases phenotype PMID:25637568
GO:0044237 Cellular metabolic process Decreases phenotype PMID:31823256; PMID:34175401
GO:0044319 Wound healing, spreading of cells Affects phenotype PMID:27206737; PMID:34175401
GO:0045454 Cell redox homeostasis Decreases phenotype PMID:30368975
GO:0045600 Positive regulation of fat cell differentiation Decreases phenotype PMID:28285642
GO:0045727 Positive regulation of translation Decreases phenotype PMID:27587023
GO:0045824 Negative regulation of innate immune response Increases phenotype PMID:32179172
GO:0046209 Nitric oxide metabolic process Affects phenotype PMID:31823256
GO:0046415 Urate metabolic process Decreases phenotype PMID:29913234; PMID:30368975
GO:0046449 Creatinine metabolic process Increases phenotype PMID:29913234; PMID:30368975; PMID:30997025; PMID:35020164
GO:0046651 Lymphocyte proliferation Affects phenotype PMID:33137424
GO:0048589 Developmental growth Affects phenotype PMID:32392305
GO:0050729 Positive regulation of inflammatory response Increases phenotype PMID:37045926
GO:0050765 Negative regulation of phagocytosis Increases phenotype PMID:32179172
GO:0050996 Positive regulation of lipid catabolic process Increases phenotype PMID:28285642; PMID:37045926
GO:0055007 Cardiac muscle cell differentiation Affects phenotype PMID:24704097
GO:0060326 Cell chemotaxis Decreases phenotype PMID:34175401
GO:0060548 Negative regulation of cell death Increases phenotype PMID:25637568
GO:0070328 Triglyceride homeostasis Decreases phenotype PMID:29913234; PMID:30368975
GO:0070994 Detection of oxidative stress Affects phenotype PMID:34175401
GO:0071735 Igg immunoglobulin complex Affects phenotype PMID:33137424
GO:0097006 Regulation of plasma lipoprotein particle levels Decreases phenotype PMID:29913234
GO:1901671 Positive regulation of superoxide dismutase activity Affects phenotype PMID:26184899; PMID:29913234; PMID:31368021
GO:1901992 Positive regulation of mitotic cell cycle phase transition Increases phenotype PMID:28285642
GO:1903284 Positive regulation of glutathione peroxidase activity Increases phenotype PMID:31368021
GO:1903591 Negative regulation of lysozyme activity Increases phenotype PMID:32179172
GO:1903787 Negative regulation of glutathione biosynthetic process Increases phenotype PMID:37045926
GO:2000439 Positive regulation of monocyte extravasation Increases phenotype PMID:37045926
DISCLAIMER

We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.