Acetonylacetone


Curated chemical-phenotype interactions from CTD
GO IDGO nameInteraction typeReference
GO:0001541 Ovarian follicle development Decreases phenotype PMID:33197454
GO:0001774 Microglial cell activation Increases phenotype PMID:32522579
GO:0006749 Glutathione metabolic process Affects phenotype PMID:32522579; PMID:32860822
GO:0007253 Cytoplasmic sequestering of nf-kappab Decreases phenotype PMID:22337490
GO:0007283 Spermatogenesis Decreases phenotype PMID:15141104
GO:0007286 Spermatid development Affects phenotype PMID:27466211
GO:0016042 Lipid catabolic process Affects phenotype PMID:32522579; PMID:32860822
GO:0030841 Positive regulation of intermediate filament polymerization Increases phenotype PMID:6361548
GO:0040011 Locomotion Affects phenotype PMID:32522579
GO:0042701 Progesterone secretion Affects phenotype PMID:33197454
GO:0061564 Axon development Affects phenotype PMID:32860822
GO:0061744 Motor behavior Affects phenotype PMID:32522579
GO:0090659 Walking behavior Affects phenotype PMID:31760062; PMID:32860822
GO:1904196 Negative regulation of granulosa cell proliferation Increases phenotype PMID:22337490
GO:1904710 Positive regulation of granulosa cell apoptotic process Increases phenotype PMID:22337490
GO:1905517 Macrophage migration Increases phenotype PMID:32860822

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We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.