| GO ID | GO name | Interaction type | Reference |
|---|---|---|---|
| GO:0006915 | Apoptotic process | Increases phenotype | PMID:30300626 |
| GO:0006974 | Cellular response to dna damage stimulus | Increases phenotype | PMID:30300626 |
| GO:0007204 | Positive regulation of cytosolic calcium ion concentration | Increases phenotype | PMID:22848001 |
| GO:0008206 | Bile acid metabolic process | Affects phenotype | PMID:28161596 |
| GO:0008283 | Cell population proliferation | Decreases phenotype | PMID:30300626 |
| GO:0010918 | Positive regulation of mitochondrial membrane potential | Decreases phenotype | PMID:22848001 |
| GO:0010940 | Positive regulation of necrotic cell death | Increases phenotype | PMID:22848001 |
| GO:0010942 | Positive regulation of cell death | Increases phenotype | PMID:28161596 |
| GO:0015721 | Bile acid and bile salt transport | Decreases phenotype | PMID:28161596 |
| GO:0016042 | Lipid catabolic process | Increases phenotype | PMID:30300626 |
| GO:0030186 | Melatonin metabolic process | Decreases phenotype | PMID:27633141 |
| GO:0051881 | Regulation of mitochondrial membrane potential | Affects phenotype | PMID:30300626 |
| GO:0090200 | Positive regulation of release of cytochrome c from mitochondria | Increases phenotype | PMID:22848001 |
| GO:1902656 | Calcium ion import into cytosol | Increases phenotype | PMID:30300626 |
| GO:1903409 | Reactive oxygen species biosynthetic process | Increases phenotype | PMID:30300626 |
| GO:1903428 | Positive regulation of reactive oxygen species biosynthetic process | Increases phenotype | PMID:22848001 |
We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.