Chromium


Curated chemical-phenotype interactions from CTD
GO IDGO nameInteraction typeReference
GO:0000041 Transition metal ion transport Increases phenotype PMID:30496737
GO:0000080 Mitotic g1 phase Affects phenotype PMID:28035397
GO:0000084 Mitotic s phase Affects phenotype PMID:28035397
GO:0000085 Mitotic g2 phase Affects phenotype PMID:28035397
GO:0001836 Release of cytochrome c from mitochondria Increases phenotype PMID:29115570
GO:0003006 Developmental process involved in reproduction Decreases phenotype PMID:32653800
GO:0004364 Glutathione transferase activity Decreases phenotype PMID:30359721
GO:0006750 Glutathione biosynthetic process Decreases phenotype PMID:30359721
GO:0006915 Apoptotic process Increases phenotype PMID:25227780; PMID:28035397; PMID:29115570
GO:0006979 Response to oxidative stress Affects phenotype PMID:30529889
GO:0010467 Gene expression Increases phenotype PMID:19595304
GO:0010468 Regulation of gene expression Affects phenotype PMID:35646058
GO:0032616 Interleukin-13 production Increases phenotype PMID:31921472
GO:0042403 Thyroid hormone metabolic process Affects phenotype PMID:38797200
GO:0042632 Cholesterol homeostasis Affects phenotype PMID:25867198
GO:0043065 Positive regulation of apoptotic process Increases phenotype PMID:24723216; PMID:38605572
GO:0044237 Cellular metabolic process Decreases phenotype PMID:28035397; PMID:29115570; PMID:31953414
GO:0048589 Developmental growth Decreases phenotype PMID:35646058
GO:0051882 Mitochondrial depolarization Increases phenotype PMID:29115570
GO:0055065 Metal ion homeostasis Decreases phenotype PMID:27592743
GO:0070328 Triglyceride homeostasis Affects phenotype PMID:25867198
GO:0070633 Transepithelial transport Increases phenotype PMID:35584729
GO:0070835 Chromium ion transmembrane transporter activity Increases phenotype PMID:36410050
GO:0071247 Cellular response to chromate Affects phenotype PMID:35547012
GO:0072593 Reactive oxygen species metabolic process Affects phenotype PMID:28035397
GO:1903047 Mitotic cell cycle process Affects phenotype PMID:28035397
GO:1903409 Reactive oxygen species biosynthetic process Increases phenotype PMID:30359721
GO:1903428 Positive regulation of reactive oxygen species biosynthetic process Increases phenotype PMID:38605572
DISCLAIMER

We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.